Medtronic Cryocath LP

Medtronic, Inc.

Medtronic Cyrocath LP

Nicolas Coulombe

Jean-Pierre Lalonde

Dan Wittenberger

Zhongping C Yang

Peter Nicholas Braido

Randal C Schulhauser

Wlodzimierz Sadzynski

Paul Stanley Addison

Shantanu Sarkar

Mina Safwat Fahim

Rachid Mahrouche

Anthony W Rorvick

Jean-Luc Pageard

John B Horrigan

William C Harding

Ioana Deac

Ross D Hinrichsen

Megan L Harris

Louis Jacob

Karl Heinz Kuck

Scott A Ransom

Randy Jordan

Monica M Bolin

Angela Burgess

Julia Schraut

Max L Balter

Martin Lacharite

Jean Pierre Lalonde

Feifan Ouyang

Julian Chun

Marcin Kowalski

A method of ablating tissue includes positioning a treatment device proximate to a target tissue area. The treatment device has an expandable treatment element. The expandable treatment element is inflated with a refrigerant during an inflation phase such that at least a portion of the expandable treatment element is in contact with the target tissue area. A first pressure measurement of the inflated expandable treatment element is recorded and compared to a predetermined pressure threshold. The refrigerant is circulated within the expandable treatment element during an ablation phase to reduce a temperature of the target tissue area to a temperature sufficient to cryoablate the target tissue area. A second pressure measurement of the expandable treatment element is recorded during the ablation phase and compared to the predetermined pressure threshold.

Contact pressure assessment for cryoballoon ablation catheters

An epicardial device, system, and method for stabilizing the left atrial appendage during a left atrial appendage ligation/occlusion procedure. A cryoadhesion device including a stabilization element is positioned within the pericardial space proximate the left atrial appendage through subxiphoid access. Once the stabilization element is in contact with the left atrial appendage, the stabilization element is cooled to a temperature that is sufficient to cryoadhere the stabilization element to the left atrial appendage. In this way, the cryoadhesion device stabilizes the left atrial appendage in order to perform left atrial appendage ligation/occlusion with a secondary medical device.

Cryoadhesive device for left atrial appendage occlusion

Novel tools and techniques are provided for implementing intelligent assistance ('IA') or extended intelligence (“EI”) ecosystem for pulmonary procedures. In various embodiments, a computing system might analyze received one or more first layer input data (i.e., room content-based data) and received one or more second layer input data (i.e., patient and/or tool-based data), and might generate one or more recommendations for guiding a medical professional in guiding a surgical device(s) toward and within a lung of the patient to perform a pulmonary procedure, based at least in part on the analysis, the generated one or more recommendations comprising 3D or 4D mapped guides toward, in, and around the lung of the patient. The computing system might then generate one or more XR images, based at least in part on the generated one or more recommendations, and might present the generated one or more XR images using a UX device.

Extended intelligence for pulmonary procedures

Devices, systems, and methods for assessing contact between a treatment element and an area of target tissue using resistive-type and/or capacitive-type contact sensing elements. In one embodiment, a medical system for determining tissue contact includes an elongate body including a distal portion and a proximal portion and a treatment element coupled to the elongate body distal portion. The treatment element may have a first expandable element, a second expandable element, the first expandable element being within the second expandable element, and at least one contact sensing element between the first and second expandable elements. In one example, the device may include a plurality of contact sensing elements arranged in a matrix or in a plurality of linear configurations. In another example, the device may include a layer of conductive microparticles or a contact-sensing film.

Cryoballoon contact assessment using capacitive or resistive sensors

A method of performing bronchial denervation of a bronchus having bronchial nerves along a portion thereof is provided. The method includes providing a cryoablation device having multiple electrodes capable of delivering electrical energy and measuring impedance. At least one bronchial nerve is stimulated with electrical energy. The electrical signals from the at least one bronchial nerve are recorded to provide a first value representative of nerve function. Cryogenic treatment energy is applied to form ice in the bronchus having a thickness to encapsulate the at least one bronchial nerve to cause a reduction in nerve function. The at least one bronchial nerve is restimulated with electrical energy. The electrical signals are recorded from the restimulated at least one bronchial nerve to provide a second value that represents diminished nerve function. The first value and the second value are compared to provide an assessment of the reduction in nerve function.

Method and apparatus for determining bronchial denervation

A catheter-based medical device including controlled refrigerant dispersion is disclosed. The device includes a fluid injection tube that carries refrigerant from a coolant supply to the distal portion of the device. A fluid dispersion unit is disposed on the distal end of the fluid tube to control the angle of distribution for refrigerant that is expelled from the fluid injection tube. Controlling the angle of distribution for the refrigerant facilitates dispersion of the fluid in a predetermined spray pattern. The disclosure further relates to cryoablation treatment systems incorporating such a catheter, and to cryoablation treatment methods for tissue treatment to address various conditions suitably treatable with cryoablation.

Spray nozzle design for a catheter

Novel tools and techniques are provided for implementing intelligent assistance ('IA') ecosystem, and, in some cases, for implementing extended reality (“XR”) for cardiac arrhythmia procedures. In various embodiments, a computing system might receive device data associated with a device(s) configured to perform a cardiac arrhythmia procedure to provide effective heart rhythm, might receive imaging data associated with an imaging device(s) configured to generate images of a portion(s) of a patient. The computing system might analyze the received device data and imaging data (collectively “received data”), might map the received data to a 3D or 4D representation of the portion(s) of the patient based on the analysis, and might generate and present (using a user experience (“UX”) device) one or more XR images or experiences based on the mapping.

Extended reality (XR) applications for cardiac arrhythmia procedures

A medical system for ablating tissue within a gallbladder having a gallbladder wall includes a medical device. The medical device includes a shaft having a proximal portion and a distal portion opposite the proximal portion, and an inflatable treatment element coupled to the distal portion of the shaft and transitionable between a first deflated free-form configuration and a second inflated coiled configuration.

Percutaneous coiled catheter design for gallbladder cryoablation

Devices, systems, and methods for maintaining cryoballoon size, cryoballoon pressure, and/or coolant flow rate based on physical characteristics of the tissue to be ablated. In one embodiment, a cryoablation system comprises: a cryoablation device, the cryoablation device including: an expandable treatment element defining an interior chamber; and a pressure sensing system at least partially within the interior chamber; a fluid flow path including at least one valve that is in communication with at least one PID device; and a control unit including processing circuitry in communication with the pressure sensing system and the at least one PID device, the processing circuitry being configured to: determine a target pressure of the expandable treatment element based on a target size of the expandable treatment element; and determine a target flow rate of coolant through the fluid flow path based on the target pressure of the expandable treatment element.

Control method for a one balloon fits all in automated mode

A system and device for cryoablation of tissue that is suitable for use within an MRI environment. The device may include an elongate body, a treatment element at the distal portion of the elongate body, and one or more pull fibers. The pull fibers may be composed of a non-ferromagnetic material, such as a polymer. Likewise, none of the other device components may be composed of a ferromagnetic material. The device may also include at least one fiber optic sensor. The elongate body distal portion may include a distal tip to which the pull fibers are directly coupled. Additionally or alternatively, the elongate body may include one or more pull fiber lumens configured to allow the pull fibers to deflect the distal portion when a pull force is exerted on the pull fibers.

MRI-compatible cryocatheters and system

A method of treating or preventing acute respiratory distress syndromes (ARDS) includes advancing a cryogenic treatment element into a target bronchus of a mammal and exchanging cryogenic energy between the target bronchus and the cryogenic treatment element for a predetermined period of time until a target temperature of the target bronchus is reached to cause neuropraxia of nerves within the target bronchus.

Apparatus and method for targeted temporary bronchial nerve modulation by cryo-ablation for prevention and treatment of acute respiratory distress syndromes

A method, system, and device for predicting lesion quality. Specifically, lesion quality may be predicted based on an assessment of pulmonary vein occlusion using injection of an impedance-modifying agent and evaluation of changes in impedance measurements recorded by an electrode located distal to an occlusion element of the treatment device used to inject the impedance-modifying agent. The quality of the occlusion may be rated based on the changes in impedance over time within the pulmonary vein. For example, the quality of the occlusion may be rated as being good, fair, or poor. This assessment may be quickly and easily communicated to an operator.

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Anjou, Canada

Nicolas Coulombe