University of California

The United States of America, As Represented by the Secretary, Department of Health and Human Services

Nick Ryba

Jon Elliot Adler

Charles S Zuker

Ken Mueller

Mark A Hoon

The invention provides nucleic acid and amino acid sequences for a novel family of taste transduction G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of taste transduction G-protein coupled receptors.

Method for identifying compounds that modulate a T2R taste receptor

Nucleic acids encoding T2R bitter taste receptors

The invention provides isolated nucleic acid and amino acid sequences of taste cell specific G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of taste cell specific G-protein coupled receptors.

Methods for identifying compounds which modulate T2R bitter taste receptors

Nucleic acid encoding a T2R taste receptor

Methods for identifying modulators of SF taste receptor signaling

Nucleic acids encoding T2R taste receptors

Nucleic acids encoding T2R, a novel family of taste receptors

Methods of screening modulators of T2R taste receptors

Method for identifying compounds modulating taste transduction

Nucleic acids encoding T2R of taste receptors

T2R, a novel family of taste receptors

SF, a novel family of taste receptors

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Bethesda, MD, United States of America

Nick Ryba