Zimmer Orthobiologics, Inc.

Garrett, Ian Ross

Li, Shuliang

Akella, Rama

Wen, Hai Bo

Acker, Dean M.

Wilhelm, Nichole

Nichole Wilhelm

Rama Akella

Hai Bo Wen

Shuliang Li

Ian Ross Garrett

Dean M Acker

A bone void filler composition is described containing an acidic mineral component that contains a calcium source and a phosphate source or a lower alkyl carboxylate source; an osteoinductive component that contains demineralized bone; and a three-dimensional, osteoconductive biologically acceptable carrier component that contains a collagenous material. The bone void filler composition may be in the form of a sponge or in the form of a paste or putty used to form a sponge or is obtained from particulated sponge, or that forms after a sponge is rehydrated. A pre-mixed bone void filler composition is described containing the acidic mineral component or the lower alkyl carboxylate source; the osteoinductive component; and a biologically acceptable carrier component that contains a liquid carrier. Methods of making and using the compositions are also described. The ratio of demineralized bone component to acidic mineral component may range from about 0.5:1 to about 80:1.

Bone void fillers

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Warsaw, IN, United States of America

Nichole Wilhelm