Cree Gmbh

Know Bio, LLC

Ideal Industries Lighting LLC

Uv Innovators, LLC

Photonmd, Inc.

Freescale Semiconductor,inc.

Ideal Industries, Inc.

Creeled, Inc.

Gogown, LLC

Nicholas William Medendorp, Jr

Bernd P Keller

Paul Kenneth Pickard

Gerald H Negley

Kurt S Wilcox

James Michael Lay

Brian L Kinnune

Ban Poh Loh

Antony Paul Van De Ven

Nathan R Snell

Eric J Tarsa

Mark Dixon

Nathan Stasko

Norbert Hiller

Katelyn P Reighard

Zongjie Yuan

Russell George Villard

James Ibbetson

Stephen Michael Grenon

Scott Eric Liddle

S Scott Pratt

Gary David Trott

Theodore D Lowes

William Laird Dungan

Mario Alberto Castillo

Peter E Lopez

Yuequan Hu

Jeremy Richard Sorenson

Tao Tong

Mark Youmans

Nathan Thomas Luck

Jeffery Michael Rosino

David T Emerson

Michael John Bergmann

David P Goelz

Randall Levy Bernard

Randolph Cary Demuynck

Adam Cockrell

Ronan Letoquin

F Neal Hunter

Rebecca McDonald

Peter Scott Andrews

Matthias Passlack

Alan J Ruud

George R Brandes

Michael James Harris

John Wesley Durkee

Andrew Dan Bendtsen

Craig D Raleigh

Dong Lu

Don Miletich

Corey Goldstein

Liqin Ni

Boris Karpichev

Ronan P LeToquin

Owen Lewis Joyce

Mark McClear

Thomas Cheng-Hsin Yuan

Fabian Jean-Daniel Rol

John Adam Edmond

Curt Progl

Benjamin A Jacobson

Mark D Edmond

Ronan P Le Toquin

Long Larry Le

Ashay Chitnis

Matthew Carl Reynolds

Max Batres

Shawn Leroux Heeter

Douglas E Keiter

Nathaniel O Cannon

Mitch Jackson

Yuming Chen

Lawrence Maurice Roberts, Jr

Virginia Porowski

Anthony Barret Smith

Bart P Reier

Randy Bernard

David Power

John C Perry

John R Rowlette, Jr

James McBryde

Michael P Laughner

Nick Hoang Nguyen

Yaote Huang

Spencer Scott Pratt

Thomas Yuan

Sandeep Pawar

Robert D Gengelbach

Daniel James VanEpps, Jr

Yankun Fu

Vasavi Mandavilli

Peter Guschl

Timothy J O'Sullivan

Todd McNeil Pope

Robert Alexander Stevenson

Jesse Andrew Melton

Katelyn Reighard Crizer

Matthew C Reynolds

Lawrence Roberts

Systems and methods for phototherapeutic modulation of nitric oxide in mammalian tissue include use of a first wavelength and first radiant flux of light to stimulate enzymatic generation of nitric oxide, and use of a second wavelength and second radiant flux of light to stimulate release of nitric oxide from endogenous stores of nitric oxide. Pulsed light and/or partially non-overlapping light impingement windows may be used. Non-coherent light impinged on tissue may include a peak wavelength in a range of from 410 nm to 440 nm in the absence of light emissions having a peak wavelength of from 600 nm to 900 nm.

Systems and methods for phototherapeutic modulation of nitric oxide

Modulated light therapy devices for treatment of dermatological disorders of the scalp are provided. An exemplary device includes a flexible printed circuit board (FPCB) supporting at least one light emitting device having an emitter height. The FPCB includes multiple interconnected panels and bending regions defined in and between at least some of the interconnected panels as to allow the FPCB to be configured in a concave shape to cover at least a portion of a cranial vertex of the patient. At least one light-transmissive layer proximate to the FPCB is configured to transmit (e.g., incoherent) light emissions generated by at least one light emitting device. At least one standoff is configured to be arranged between the FPCB and the scalp of the patient, wherein the at least one standoff includes a standoff height that exceeds the emitter height.

Phototherapy devices for treatment of dermatological disorders of the scalp

Methods and related devices for impinging light on tissue, for example within a body of a patient, to induce various biological effects are disclosed. Biological effects may include at least one of inactivating and/or inhibiting growth of one or more pathogens, upregulating a local immune response, stimulating enzymatic generation of nitric oxide to increase endogenous stores of nitric oxide, releasing nitric oxide from endogenous stores of nitric oxide, and inducing an anti-inflammatory effect. Wavelengths of light are selected based on intended biological effects for one or more of targeted tissue types and targeted pathogens. Light treatments may provide multiple pathogenic biological effects, either with light of a single wavelength or with light having multiple wavelengths. Devices and methods for light treatments are disclosed that provide light doses for inducing biological effects on various targeted pathogens and targeted tissues with increased efficacy and reduced cytotoxicity.

Phototherapeutic light for treatment of pathogens

A surface covering member includes a wrapper panel and pliable sheet material with at least one liquid-penetration-resistant layer. The wrapper panel may at least partially envelop the pliable sheet material when the pliable sheet material is compacted. At least one accordion fold may be provided along one or more peripheral edges, optionally with the wrapper panel forming a pouch. First and second wrapper panels may be arranged at first and second positions of the pliable sheet material. A wrapper panel may be a continuous extension of the pliable sheet material, and at least one selectively deployable adhesive tab at a peripheral edge of the wrapper panel affixes the wrapper panel against the pliable sheet material when the surface covering member is in a non-compacted state, and at least partially envelops the pliable sheet material when it is compacted by rolling and/or folding to maintain the compacted pliable sheet material in the at least partially enveloped state.

Compactable surface covering member and method for compacting the same

Embodiments provide methods and apparatus for fabricating blood products, such as platelet-rich plasma, containing elevated concentrations of growth factors such as platelet derived growth factor. The platelet-rich plasma can be autologous, and the concentration of growth factors (e.g., platelet derived growth factor) is elevated relative to other samples isolated from the same subject. The platelet-rich plasma can be used to promote tissue regeneration, including wound healing, joint repair, hair growth, and the like. The compositions can be combined with stem cells and used to treat disorders otherwise treated with stem cells. The growth factors present in the samples can direct the differentiation of the stem cells.

Photoactivated blood products and methods and apparatus for fabrication and use of same

Systems, devices, and related methods for phototherapeutic treatment of skin, and more particularly phototherapeutic treatments for skin conditioning and/or the treatment of skin wrinkles are disclosed. Certain aspects relate to impinging light having a first peak wavelength on skin tissue at a first radiant flux, a second peak wavelength on the skin tissue at a second radiant flux, and, optionally, a third peak wavelength on skin tissue at a third radiant flux. The first wavelength may be selected to produce nitric oxide in the skin and/or to release endogenous stores of nitric oxide; the second wavelength may be selected to promote collagen production. Certain methods involve impinging light having a third peak wavelength that may be selected to reduce inflammation. Devices are disclosed that include combinations of housings, light-transmissive elements, and flexible substrates that are configured to deliver such light to one or more targeted areas.

Devices and related methods for phototherapeutic treatment of skin

Ultraviolet (UV) light emission devices and related methods of use. The UV light emission devices disclosed herein are particularly suited for use in disinfecting surfaces and air. The UV light emission devices disclosed herein can be provided in the form factor of a handheld device that is easily held and manipulated by a human user. The human user can manipulate the handheld UV light emission device to decontaminate surfaces, air, and other areas by orienting the handheld UV light emission device so that the UV light emitted from its light source is directed to the area of interest to be decontaminated.

Ultraviolet (UV) light emission device employing visible light for operation guidance, and related methods of use, particularly suited for decontamination

An LED package comprising a submount having a top and bottom surface with a plurality of top electrically and thermally conductive elements on its top surface. An LED is included on one of the top elements such that an electrical signal applied to the top elements causes the LED to emit light. The electrically conductive elements also spread heat from the LED across the majority of the submount top surface. A bottom thermally conductive element is included on the bottom surface of said submount and spreads heat from the submount, and a lens is formed directly over the LED. A method for fabricating LED packages comprising providing a submount panel sized to be separated into a plurality of LED package submounts. Top conductive elements are formed on one surface of the submount panel for a plurality of LED packages, and LEDs are attached to the top elements. Lenses are molded over the LEDs and the substrate panel is singulated to separate it into a plurality of LED packages.

Light emitting diode package and method for fabricating same

Systems and methods for a high output, high color quality light are disclosed. In some embodiments, such a light may include a light fixture including one or more LEDs configured to output a cumulative light output; wherein the cumulative light output comprises an intensity of greater than or equal to 10,000 lumens; and wherein the cumulative light output comprises a CRI of at least 90.

Systems and methods for high output, high color quality light

Ultraviolet (UV) light emission device employing visible light for target distance guidance, and related methods of use, particularly suited for decontamination

Growing community of inventors

Raleigh, NC, United States of America

Nicholas William Medendorp, Jr