Northern Illinois University

Protonvda LLC

Fermi Research Alliance, LLC

University of Wollongong

Board of Trustees of Niu

Nicholas Karonis

Kirk Duffin

John Winans

Don F Dejongh

Ethan A Dejongh

Scott N Penfold

George Coutrakon

Vishnu Zutshi

Bela Erdelyi

Victor Rykalin

Paul Rubinov

Kevin Naglich

Caesar Ordoñez

Don F DeJongh

Ethan A DeJongh

Caesar Ordonez

Caesar E ORDOÑEZ

A novel method and a related system are configured to place measured trajectories into a voxel space, which moves with respect to a particle detector system. The trajectories are measured in a detector reference frame. The voxel space, typically fixed with respect to the object being imaged, is tracked optically with markers and a camera system. A decipherable correlation is established between a set of markers and a set of detector elements. This correlation provides coordinate transformation definitions to place the trajectories into the voxel space in medical imaging, treatment planning, and/or therapeutic applications. The novel method provides a clever process to register an optical tracking system with a particle detector system, which improves quality assurance, accuracy, speed, and operating cost efficiencies of ion, particle, and/or radiation-based imaging, treatment planning, or therapies. This novel method may be utilized in proton imaging, helium imaging, other ion-based imaging, or x-ray imaging.

Method to register an optical tracking system with a particle detector system

A computer-implemented system and method for generating a medical image is provided. In some embodiments, the medical image is generated by determining a location and an alignment for a first tracking detector with respect to a particle beam system. The direction of a beam generated from the particle beam system is determined. A first position of a first particle from a detected particle hit on the first tracking detector is also determined. A determination is made as to a first residual range of the first particle from a detected particle hit on a residual range detector. The system reconstructs a path for the first particle based on the location, the alignment, the first position, and the first residual range of the first particle. The resulting medical image that is generated by the system is based on the reconstructed path for the first particle.

Processing pipeline for prompt particle image reconstruction

A proton computed tomography (pCT) detector system, including two tracking detectors in sequence on a first side of an object to be imaged, two tracking detectors in sequence on an opposite side of the object to be imaged, a calorimeter, and a computer cluster, wherein the tracking detectors include plastic scintillation fibers. All fibers in the detector system are read out by Silicon Photomultipliers (SiPM). A method of imaging an object by emitting protons from a source through two tracking detectors, through and around the object, and through two opposite tracking detectors, detecting energy of the protons with a calorimeter, and imaging the object.

High performance computing for three dimensional proton computed tomography (HPC-pCT)

High performance computing for three dimensional proton computed tomography (HPC-PCT)

Growing community of inventors

West Chicago, IL, United States of America

Nicholas Karonis