Smith + Nephew

Smith & Nephew Orthopaedics Ag

Smith Nephew Asia Pacific Pte. Limited

Nicholas John Cotton

Paul Alexander Torrie

Malcolm Brown

Michael Andrew Hall

John M Lipchitz

Rod Berube

David F Farrar

John Eric Brunelle

Melissa Jane Egan

Steven William Astorino

Emma J Wright

David L Brumfield

Horacio Montes De Oca Balderas

Graeme Howling

Saad Abdul Majeed Ali

Steve Fenwick

Sorrel Wolowacz

Saad Ali

Emma Wright

David Farrar

Fixation devices for tissue repair, for example sutures, surgical arrows, staples, darts, bolts, screws, buttons, anchors, nails, rivets, or barbed devices comprise at least one of angiogenic material; angiogenic precursor material which is capable of breaking down in vivo to form angiogenic material; or tissue-engineered material, which tissue-engineered material is capable of producing angiogenic material. In a preferred form, the material is incorporated into a polymer matrix having predetermined hydrophobicity to allow controlled release of angiogenic materials such as butyric or hydroxybutyric acid or salts thereof. Polymer matrix compositions comprising angiogenic materials and methods for tissue repair are also provided.

Fixation devices for tissue repair

The present disclosure relates to an anchor for fixating a tissue graft to bone. The anchor includes a through hole extending an entire length of the anchor and a polymer composition having shape memory qualities. Other anchors and methods for fixating a tissue graft to bone are also disclosed.

Graft fixation

Tissue fixation devices are provided. The devices include a first component and a second component, the components having different rates of in vivo degradation. The first component and second component are arranged so that, upon degradation of one of the components, the other component provides a scaffold into which bone can grow.

Tissue repair and replacement

A new material was assessed in a patellar reattachment model in sheep and evaluated using histology and biomechanical testing. Overall, these materials showed they produced minimal reactivity histologically. The new material had higher failure strength overall compared to a previous study with the control material as repairs completed with PLG/CS/TCP anchors were significantly stronger compared to repairs with PLLA anchors.

Bioabsorbable polymers

Described herein are biocompatible compositions that contain a copolymer and a filler material. In particular, described herein are compositions that include a copolymer and a filler which may be a calcium salt. Also described herein are methods in which the compositions are used to attach soft tissue to bone.

Biocompatible, implantable material comprising flexible, elongate tape and a plurality of elongate elements, each elongate element being aligned along and independently translatable in the longitudinal direction of the tape; implants manufactured from this material, for the partial or total replacement or reinforcement of connective tissue such as ligament, cartilage, bone, meniscus tendon, skin.

Implants for connective tissue reconstruction

Growing community of inventors

Westborough, MA, United States of America

Nicholas John Cotton