Medtronic Vascular, Inc.

Medtronic Vascular Galway Limited

Medtronic, Inc.

Medtronic Cv Luxembourg S.a.r.l.

Twelve, Inc.

Ave Connaught

Medtronic Ave, Inc.

Medtronic Ventor Technologies Ltd.

Niall F Duffy

John Gallagher

Gavin Kenny

Declan P Costello

Kate Corish

Marc A Anderson

Marian Creaven

Patrick Griffin

Frank Harewood

Gerry Oliver McCaffrey

Jeffrey D Sandstrom

Jason L Quill

Ana Menk

Frank White

Joshua J Dwork

Edmond Sheahan

Evelyn Birmingham

Deirdre Bridget McGowan Smyth

Constantin Ciobanu

Donna Barrett

John Milroy

Paul Devereux

Noel Coyle

Bernard Patrick Mulvihill

Fabio Bartolozzi

Herinaina Rabarimanantsoa Jamous

Darren A Janzig

Patrick Edward Macaulay

Philip Jon Haarstad

Igor Kovalsky

Shyam Gokaldas

Glenn C Stante

Marian Patricia Lally

Daniel M Gelfman

Stephen J Peter

Noam Miller

Paul T Rothstein

David M Farascioni

Michael Gloss

Jay T Rassat

Nathan Knutson

Aran Murray

Ronan Thornton

Rodney Bell

Ronan Rogers

Rishi Manda

Kenneth Dale Warnock, Jr

Gerry Clarke

David O'Toole

Adam Fitzgerald

Luke McCartney

James R Keogh

Kevin M Mauch

Yossi Tuval

Lone Wolinsky

Mark Casley

Paraic Frisby

Sarah E Ahlberg

Stephen Montgomery

Kieran Cunningham

Patrick Duane

Amir David Loshakove

David Quinn

Brendan Cunniffe

Gil Naor

Arvi Penner

Oisin Cooney

Daniel Glozman

Matthew Rust

Yves Bayon

Robert H Murray

Adam Shipley

Alexander J Hill

Grainne Teresa Carroll

Hubert K Yeung

Geoffrey Orth

Benjamin Wong

Ahmed M Elmouelhi

Matthew Fleming

Paula McDonnell

Karan Punga

Elliot J Howard

Karl Olney

Elizabeth A Schotzko

Devin Gosal

Luke Lehmann

Thomas Farrell

Jeffrey Madden

Kevin O'Sullivan

Terry A Guinan

Kevin Boyle

Damian Carr

Alfonso D'Alessandro

Misha Young

Paul Mearns

Ashish Varma

Ciaran McGuinness

Richard Gribbons

Yueqiang Xue

Scott Janis

A modular valve prosthesis includes an inflow stent, a valve component including a valve stent and a prosthetic valve, and an outflow stent. In a radially compressed delivery configuration, an inflow end of the valve stent is separated from an outflow end of the inflow stent and an outflow end of the valve stent is separated from an inflow end of the outflow stent. In a radially expanded deployed configuration, the inflow end of the valve stent is in contact with the outflow end of the inflow stent and the outflow end of the valve stent is in contact with the inflow end of the outflow stent. A delivery system includes a capsule including first, second and third sections and flexible first and second bands between respective sections. The modules of the modular valve prosthesis are aligned with the sections and gaps between the modules are aligned with the bands.

Modular valve prosthesis, delivery system, and method of delivering and deploying a modular valve prosthesis

A prolapse prevention device formed by a continuous wire-like structure having a first end and a second end disconnected from each other. The continuous wire-like structure is substantially straight in a delivery configuration. The prolapse prevention device in a deployed configuration includes a centering ring of the continuous wire-like structure configured to seat adjacent to and upstream of an annulus of a heart valve in situ, a vertical support of the continuous wire-like structure which extends from the centering ring and includes an apex configured to seat against a roof of an atrium in situ, and a leaflet backstop of the continuous wire-like structure extending radially inward from the centering ring and configured to contact at least at least a first leaflet of the heart valve in situ to exert a pressure in a downstream direction on the first leaflet to prevent the first leaflet from prolapsing into the atrium.

Prolapse prevention device and methods of use thereof

A loading device includes a locking collar assembly including a proximal end, a distal end, and a loading channel formed between the proximal end and the distal end. The device also includes a loading funnel coupled to the distal end of the locking collar assembly at a proximal end of the loading funnel. The loading funnel is configured to store a collapsible medical device in a partially collapsed state within a tapered interior volume of the loading funnel. The tapered interior volume decreases in volume from a distal end of the loading funnel to the proximal end of the loading funnel.

Integrated loading and storage system for implantable medical devices

The present disclosure relates to delivery devices for transcatheter stented prosthesis loading, delivery and implantation. The delivery devices provide a loaded delivery state in which the stented prosthesis is loaded and compressed over the delivery device. The compression of the stented prosthesis can be adjusted with one or more elongate tension members, which extend around the stented prosthesis and proximately to an actuation and release assembly that can be provided as part of a handle assembly. The delivery device can be manipulated to adjust tension in the tension members to permit the stented prosthesis to compress, self-expand, and ultimately release from the shaft assembly. In some embodiments, the tension in one or more tension members is adjusted with one or more actuation and release assemblies.

Tension member routing designs to achieve transcatheter stented prosthesis compression

Distal tips for use with delivery catheters are disclosed that are configured to facilitate deflection of the catheters as they are advanced through the vasculature to a desired treatment site. Distal tips so configured realize one or more of the objectives of safer, more accurate steering of the catheter through the vasculature.

System and method for deflecting a delivery catheter

A valve prosthesis and methods for implanting the prosthesis are provided. The prosthesis generally includes a self-expanding frame and two or more engagement arms. A valve prosthesis is sutured to the self-expanding frame. Each engagement arm corresponds to a native mitral valve leaflet. At least one engagement arm immobilizes the native leaflets, and holds the native leaflets close to the main frame. The prosthetic mitral valve frame also includes two or more anchor attachment points. Each anchor attachment point is attached to one or more anchors that help attach the valve prosthesis to the heart.

Prosthetic mitral valve and delivery method

A heart valve therapy system including a delivery device and a stented valve. The delivery device includes an outer sheath, an inner shaft, an optional hub assembly, and a plurality of tethers. In a delivery state, a stent frame of the prosthesis is crimped over the inner shaft and maintained in a compressed condition by the outer sheath. The tethers are connected to the stent frame. In a partial deployment state, the outer sheath is at least partially withdrawn, allowing the stent frame to self-expand. Tension in the tethers prevents the stent frame from rapidly expanding and optionally allowing recapture. Upon completion of the stent frame expansion, the tethers are withdrawn.

Systems, devices and methods for transcatheter valve delivery

Embodiments hereof relate to a delivery system for a transcatheter valve prosthesis, the delivery system having an integral centering mechanism to circumferentially center both the delivery system and the valve prosthesis within a vessel at the target implantation site. The centering mechanism may include expandable wings that may be selectively aligned with openings formed through a sidewall of an outer shaft of the delivery system, a coiled wing that may be selectively exposed through an opening formed through a sidewall of an outer shaft of the delivery system, a plurality of elongated filaments extending through a plurality of lumens of an outermost shaft of the delivery system that may be selectively deployed or expanded, an outer shaft that includes at least one pre-formed deflection segment formed thereon, a tool having a deployable lever arm, and/or a plurality of loops deployable via simultaneous longitudinal and rotational movement.

Delivery system having an integral centering mechanism for positioning a valve prosthesis in situ

In some examples, a medical device includes a substrate defining a central port configured to provide surgical access to a surgical site opposite the substrate during a surgical procedure; and a plurality of reinforcement features disposed around the central port, wherein each reinforcement feature of the plurality of reinforcement features is configured to receive a suture, and wherein the plurality of reinforcement features are positioned to cause the substrate to tighten around the central port in response to tension being applied to ends of at least one suture connecting two or more reinforcement features.

Surgical site support article

Devices, systems, and methods for crimping a medical device are disclosed. More specifically, the present disclosure relates to devices, systems, and methods for reducing the diameter of a collapsible heart valve prosthesis to be loaded onto a delivery device. The devices, systems, and methods using at least one funnel to crimp the heart valve prosthesis and load it onto the delivery system.

Devices and methods for crimping a medical device

In some embodiments, a medical device delivery system includes a catheter and a retainer. The retainer can be engaged with the medical device to restrain relative movement of the medical device in one or more axial and/or radial directions. A variety of retainers and retainer systems are disclosed, many of which can reliably disengage the medical device from the retainer. Methods for using the medical device delivery system are also described.

Medical device delivery system and methods of delivering medical devices

A fluid diversion device configured in accordance with embodiments of the present technology can include, for example, a housing including channels configured to receive respective tubes, and a bore that extends laterally across the plurality of channels. The device can include an occlusion member disposed in the bore, where rotation of the occlusion member selectively occludes either a first subset of tubes or a second subset of tubes. The device can include an actuator that enables rotation of the occlusion member to a first position and a second position such that the first subset of tubes and the second subset of tubes are alternatively occluded in the first position or the second position for fluid communication in different directions relative to chambers of a delivery device operable to deploy and recapture the medical device.

Fluid diversion devices for hydraulic delivery systems and associated methods

A prolapse prevention device formed by a continuous wire-like structure having a first end and a second end disconnected from each other. The continuous wire-like structure of the prolapse prevention device is substantially straight in a delivery configuration. The prolapse prevention device in a deployed configuration includes a centering ring of the continuous wire-like structure configured to seat adjacent to and upstream of an annulus of a heart valve in situ, a vertical support of the continuous wire-like structure which extends from the centering ring and includes an apex configured to seat against a roof of an atrium in situ, and a leaflet backstop of the continuous wire-like structure extending radially inward from the centering ring and configured to contact at least at least a first leaflet of the heart valve in situ to exert a pressure in a downstream direction on the first leaflet to prevent the first leaflet from prolapsing into the atrium.

A medical device delivery system can include a dilator including a tip having a taper in a distal direction, a coupler, and a flap that radially protrudes from the tip. The flap can be configured to bend against a body lumen to cover at least a portion of the delivery system when the dilator is tracked through the body lumen. A medical device delivery system can include a dilator including a tip having a lumen and a coupler having a lumen. The coupler can be configured to securely connect to the tip such that the lumen of the tip is aligned with the lumen of the coupler to allow a guide wire to pass therethrough. Methods for loading a medical device into a delivery catheter are also disclosed.

Medical device delivery system and methods of delivering a medical device

Growing community of inventors

Co. Galway, Ireland

Niall F Duffy