Wisconsin Alumni Research Foundation

Ngoc Nhi Le

William Leo Murphy

David Belair

Matthew Brian Parlato

Michael P Schwartz

Michael W Toepke

Stefan Zorn

William T Daly

Eric Huy Dang Nguyen

Connie Sue Chamberlain

Hamisha Ardalani

Matthew Zanotelli

Nicholas Impellitteri

James A Molenda

David Gregory Belair

Vascular endothelial growth factor VEGF-sequestering hydrogel microspheres that have been prepared to selectively bind VEGF from blood products are disclosed herein. In one particular embodiment, the microspheres bind VEGF as part of an intra-operative process such that the growth factor can be removed from the blood products before the products are used in a clinical procedure.

Hydrogel microspheres containing peptide ligands for growth factor regulation in blood products

Hydrogel arrays, methods for preparing hydrogel arrays and methods for screening cell-substrate interactions using the hydrogel arrays are disclosed. Advantageously, the hydrogel arrays include individual hydrogel posts that are completely isolatable, allowing for systematic and independent control of the chemical composition and physical dimensions of each hydrogel post.

Covalently-immobilized hydrogel arrays in multi-well plates

Hydrogel Compositions and methods of using hydrogel compositions are disclosed. Advantageously, the hydrogel compositions offer the ability to rapidly screen substrate components for influencing cell attachment, spreading, proliferation, migration, and differentiation. In particularly suitable embodiments, the hydrogel compositions of the present disclosure may be used to promote tubulogenesis of endothelial cells.

Hydrogel compositions for use in promoting tubulogenesis

Hydrogel compositions and methods of using hydrogel compositions are disclosed. Advantageously, the hydrogel compositions offer the ability to promote cellular expansion and/or cellular differentiation of various cells.

Hydrogel compositions for use in cell expansion and differentiation

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Norcross, GA, United States of America

Ngoc Nhi Le