Warsaw Orthopedic, Inc.

Mcneil-ppc, Inc.

Johnson & Johnson Products, Inc.

Zavation Medical Products, LLC

Bonewax, LLC

Nels J Lauritzen

Lawrence A Shimp

Brent Mitchell

Brent S Mitchell

Jeffrey Bowman Johnson

Stephen Russak

Daniel Formosa

Tucker A Viemeister

Michael L Jaffe

Martha Davis

John T Ulman

Patricia A Moore

Barry E Constantine

Jeannie Gerth

Tamara Thomsen

Hsiu Ying Sherry Wang

Abdulhafez A Selem

Charles M Schiff

Jeffrey Johnson

Sherry Hsiu-Ying Wang

A biocompatible material for bone repair is described. The bone repair composition includes a mixture of a type I collagen, a type I collagen-glycosaminoglycan coprecipitate, tricalcium phosphate; and bioactive glass. Methods of using the composition for bone repair, and a kit for the bone repair composition are also described.

Bone repair composition and kit

A bone pore or void filling composition is described. The composition includes a mixture of: a type I collagen and/or a type I collagen-glycosaminoglycan coprecipitate; a blend of polyethylene glycol polymers having different molecular weights; a bone growth stimulator; and bioactive glass. A kit for containing the bone pore or void filling composition, and methods for using the composition to fill a bone pore or void are also described.

Bone putty for bone pore and void filling

Foam-formed collagen strands and methods for forming strands involve depositing a dispersed solution of an isolated cleaned, de-fatted, enzymatically-treated (or non-enzyme treated) human-derived collagen product having a preserved amount of its natural constituents into grooves of a grooved plate, and processing the dispersed collagen product to provide a foam-formed collagen strand. Foam-formed collagen strands may be processed into threads having a matrix of reticulated pores to conduct biological materials in and through the strand, the collagen of the collagen strand comprising isolated, enzymatically-treated human derived collagen having a preserved amount of its natural collagen constituents.

Foam-formed collagen strand

A composition includes bone and collagen, wherein the collagen has been acid treated, and cross-linked via dehydrothermal treatment or by a cross-linking agent (e.g., a citric acid derivative) under a compressive force of at least approximately 40 MPa.

Bone/collagen composites and uses thereof

Purifying human derived collagen from human tissue includes treating harvested human tissue with an enzyme to form a collagen product, deactivating the enzyme with a non-alkaline enzyme deactivation solution, and collecting the collagen product resulting from the enzyme treatment, where the collected collagen product includes a preserved amount of its natural collagen constituents. Various medical implants can be formed using the isolated, enzymatically-treated human derived collagen having an amount of its natural collagen constituents preserved, and may include implantable sponges, patches, tubes, structural supports and coatings, and which may be used for repair, barrier, support and/or stabilization purposes.

Methods for collagen processing and products using processed collagen

Compositions and methods for treating and healing injured soft tissues such as tendons and ligaments are provided. The composition may be a wrap comprising human collagen in the form of a sheet. The human collagen has been processed so that is retains proteins that are associated with it in its natural state. The sheet may optionally be coated on one or more sides with one or more of additional human collagen, therapeutic agents, additional soft tissue growth factors or hydroxyapatite.

Soft tissue wrap

Fenestrated wound repair scaffolds and methods for forming scaffolds involve dispersing human collagen having a preserved amount of native constituents in solution, depositing the human collagen dispersion in a tray, forming openings in the collagen dispersion and removing the liquid component to form a fenestrated wound repair scaffold. Fenestrated wound repair scaffolds include a network of openings passing linearly through the wound repair scaffold to form channels for cells to pass into so as to form a series of cell formations therein.

Fenestrated wound repair scaffold

The present invention provides methods and compositions involving resorbable hemostatic agents that have the essential absence of microfibrillar collagen. Resorbable hemostatic agents of the present invention comprise polyethylene glycol, which controls bleeding in tissue and does not delay or interfere with healing. The resorbable hemostatic agents of the present invention are biodegradable and biocompatible agents that effectively control bleeding in bone and other tissue without interfering with the subsequent healing of the tissue.

Hemostatic compositions and methods

Absorbent products having integral belt means for retaining the absorbent product in a position to absorb body fluids are disclosed. In a preferred embodiment, a napkin is provided wherein straps are cut from the material of the napkin. These straps are then tied around the body of the user when the napkin is applied. The straps are flexible enough to allow them easily to be tied to each other on the side. The straps may or may not be retained by the waistband of an undergarment. Alternatively, a second embodiment is provided wherein long flap-like straps extend longitudinally away from the transverse ends of the absorbent product. These straps are then engaged by the elastic waistband on an undergarment, to retain the napkin in place. Methods of manufacturing absorbent products are also disclosed.

Integrally belted absorbent products

This invention relates to polymer film or foam coatings for the covers of absorbent articles. More particularly, this invention relates to absorbent products and processes for making in situ foamed polymer coatings which give an opaque, soft, dry and clean-appearing water-permeable cover to absorbent products such as sanitary napkins, diapers and the like.

Method for making absorbent articles having printed polymer coatings

Printed polymer coatings and method for making same

A method of making an absorbent product in which pressure sensitive adhesive is used to attach the product to a user's undergarment. The product does not require release paper to protect the adhesive from unintended contact prior to use. The product is made by forming depressions in a fluid impervious barrier so as to create raised areas in the barrier that protect the adhesive. The depressions may be formed in the garment facing surface of the barrier and the adhesive applied within the depressions so that the raised areas adjacent the depressions protect the adhesive. Alternatively, the depressions may be formed in the surface of the barrier opposite the garment facing surface so as to create raised areas in the garment facing surface and the adhesive applied adjacent the raised areas.

Method for making an absorbent product having integrally protected

A continuous process for manufacturing absorbent pads is disclosed which comprises providing a fibrous web material and applying a fluid absorbent cover and a fluid impermeable barrier layer thereto in situ. In preferred embodiments, the pads are securable to fluid-protected surfaces by means of an adhesive on the barrier layer's outer surface.

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Piscataway, NJ, United States of America

Nels J Lauritzen