Csir

Aeci Limited

Neil Stockenstrom Gardiner

Dean Brady

Christopher John Parkinson

Stephanus Francois Marais

Jennifer Ann Chaplin

Lucia H Steenkamp

Justin Jordaan

Melanie Daryl Evans-Dickson

Etienne Van Eeden Skein

Christa Maria Jungmann

Thebeeapelo John Khaile

Owen Lungile Njamela

Dana Helen Braithwaite

Deborah Nicole Davidson

Shavani Reddy

Butana Andrew Mboniswa

Madrie Portwig

Robin Kumar Mitra

Isak Bartholomeus Gerber

Clinton Simpson

An emulsion-derived particle comprises a lattice of polymeric strands cross-linked by means of a cross-linking agent, and interstitial openings adjacent and around the strands. Functional groups are provided on the lattice and proteins and/or modified proteins can react with these, thereby to be bonded to the lattice and hence immobilized.

Emulsion-derived particles

A process of separating a single desired stereoisomer from a racemic mixture of eight stereoisomers of a compound of formula (III), wherein Rrepresents an isopropanol group, an isopropyl group or an isopropylene group, includes the steps of: contacting the racemic mixture in a suitable organic solvent with an esterifying agent and a stereospecific enzyme which stereoselectively esterifies the &#x2014;OH group of the desired stereoisomer, for a time sufficient to convert a desired percentage of the desired stereoisomer to a compound of formula (IV), wherein Ris as defined above and Ris an alkyl or an aryl group, to give a first reaction product including the compound of formula (IV), the organic solvent, the unconverted stereoisomers of the compound of formula (III), excess esterifying agent and by-products of the reaction; and separating the compound of formula (IV) from the first reaction product. The process is of particular application for the production of (&#x2212;)-menthol

Process for preparing (-) menthol and similar compounds

A process for the production of disubstituted propionic acid derivatives which are intermediates in the synthesis of .alpha.-arylpropionic acids such as naproxen, involves the reaction of a naphthalene derivative such as 2-methoxynaphthalene, with an alkylating agent such as an alkyl pyruvate in the presence of a catalyst, and then dehydrating and hydrogenolising, or directly hydrogenolising, or derivatising and then hydrogenolising the product thereof, to produce the desired compound.

Synthesis and resolution of propionic acid derivatives

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Pretoria East, South Africa

Neil Stockenstrom Gardiner