Astrazeneca Ab

Neil James Hale

Sheila Irene Hauck

Michael Barry Gravestock

Compounds of the formula (I), or a pharmaceutically-acceptable salts, or in-vivo-hydrolysable esters thereo Formula (I): wherein N-HeT is for example triazolyl; Q is for example phenyl or pyridyl, substituted with: T is for example selected from (TAa1 to TAa12) such as (TAa1) and (TAa5): R, R, Rare for example selected from hydrogen, (1&#x2013;4C)alkyl, (1&#x2013;4C)alkoxy-carbonyl, (1&#x2013;4C)alkanoyl and carbamoyl; processes for making them, compositions containing them and their use as antibacterial agents are described.

Antibacterial oxalidinones

Compounds of the formula (I), or a pharmaceutically-acceptable salts, or in-vivo-hydrolysable esters thereof, wherein: N&#x2014;HET is for example triazolyl substituted with R; Ris for example optionally substituted (1-4C)alkyl; Q is for example phenyl or pyridyl, substituted with T; T is for example selected from (TAa1 to TAa12) such as (TAa1 and TAa5); formula (II): R, R, Rare for example selected from hydrogen, (1-4C)alkyl, (1-4C)alkoxycarbonyl, (1-4C)alkanoyl and carbamoyl; processes for making them, compositions containing them and their use as antibacterial agents are described.

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Macclesfield, United Kingdom

Neil James Hale