Novartis Ag

F. Hoffmann-la Roche Ag

Neil Cammish

John Paul Palmer-Felgate

Mark Horlock

Congyi Huang

Adrian Von Muralt

Mayumi Naito Bowen

Markus Hemminger

Oliver Shergold

Andrew Bryant

Cyrille Blintz

Claudio Rossi

Jacques Appy

Gianluca Tordi

Joshua Horvath

Guido Dress

A prefilled syringe is disclosed that includes a barrel, a stopper displaceable within and defining a sealed chamber in an interior of the barrel, a liquid filled in the chamber of the barrel, and a plunger extending within the barrel. The stopper expels the liquid out of the barrel via an orifice when being forwarded towards the orifice by the plunger such that a volume of the chamber is reduced. The plunger includes a proximal portion, a distal portion and a rod portion extending between the proximal portion and the distal portion. The plunger is shaped to form a pathway between an opening of the barrel and a segment where the proximal portion of the plunger is neighboring the stopper such that a sterilizing agent can be provided through the opening of the barrel to the segment where the proximal portion of the plunger is neighboring the stopper.

Prefilled syringe and method of sterilizing a prefilled syringe

An automatic drug delivery device, for dispensing a fluid medicament, includes: a longitudinal housing; a removable cap; a syringe assembly having a hollow syringe body and an injection needle; and a drive mechanism. The loaded drive mechanism is operatively coupled with a safety shield movable within the longitudinal housing. The safety shield is biased into a proximal position in which it protrudes out of the proximal end of the longitudinal housing in order to cover a needle tip of the injection needle. The safety shield is movable into a distal position in which the injection needle is exposed for injection. The device includes a feedback mechanism providing a visual feedback to the user indicating an actual state of operation. The feedback mechanism includes a visual indicator which appears in a transparent window on the distal end of the housing.

Automatic drug delivery device

Injection device

Growing community of inventors

Manchester, United Kingdom

Neil Cammish