Apse, Inc.

Other

Neena Summers

Juan Pedro Arhancet

Juan Pedro Humberto Arhancet

Kimberly Delaney

Kathleen B Hall

Edward Oates

Charles A McWherter

Yiqing Feng

Nicholas R Staten

John P Mc Kearn

Philip R Streeter

Susan L Woulfe

Nancy I Minster

John C Minnerly

Novel processes and compositions are described which use viral capsid proteins resistant to hydrolases to prepare virus-like particles to enclose and subsequently isolate and purify target cargo molecules of interest including nucleic acids such as siRNAs and shRNAs, miRNAs, messenger RNAs, small peptides and bioactive molecules.

Compositions and methods using capsids resistant to hydrolases

Processes and compositions to produce, package, and purify virus like particles containing heterologous cargo molecules utilizing self assembling proteins and protease treatment coupled with simple precipitation and filtration methods are described.

Process for purifying VLPs

Disclosed are novel multi-functional chimeric hematopoietic receptor agonist proteins, DNAs which encode the multi-functional chimeric hematopoietic receptor agonist proteins, methods of making the multi-functional chimeric hematopoietic receptor agonist proetiens and methods of using the multi-functional chimeric hematopoietic receptor agonist proteins.

Multi-functional chimeric hematopoietic receptor agonists

Growing community of inventors

St. Louis, MO, United States of America

Neena Summers