Danisco US Inc.

The Procter Gamble Company

Genencor International, Inc.

Neelam S Amin

David Aaron Estell

Ayrookaran J Poulose

Katherine D Collier

Walter Weyler

Melodie Estabrook

Richard Ray Bott

Scott Douglas Power

Brian Frederick Schmidt

Bryan P Fox

Brian E Jones

Marguerite A Cervin

Gudrun Vogtentanz

Edward M Concar

Gregory Scot Miracle

Jeffrey John Scheibel

Philip Frank Souter

Jian Yao

Gregory Marshall Whited

James T Kellis, Jr

Marc Kolkman

Lilia Maria Babe

Hiroshi Oh

Wolfgang Aehle

Luis Gustavo Cascao-Pereira

Casper Vroemen

Glenn Steven Ward

Eva Maria Perez-Prat Vinuesa

Sandra W Ramer

Katherine Augustyn

Marc Eric Gustwiller

Klaus Liebeton

Joshua Roy Basler

Viktor Alekseyev

Matthew Grant Boston

Alexander Pisarchik

Euan John Magennis

David John Tarbit

David Marquez

Luis Gustavo Cascão-Pereira

Matthew G Boston

Rei Otsuka

Priyanka Chandrasekaran

Phillip Frank Souter

James T Kellis

Maguerite A Cervin

Gudrun Vogentanz

Brian Edward Jones

Viktor Yuryevich Alekseyev

James T Kellis Jr

Jr James T Kellis

Michelle Jackson

David Edward Wildes

Jeffrey Wayne Munos

Ayrookaran Joseph Poulose

Edwin W Lee

Victoria Huang

Geetha Veeramuthu

The present invention provides serine protease variants produced there from. Specifically, the present invention provides serine protease variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants.

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The present invention provides serine protease variants, more specifically subtilisin variants produced there from. Specifically, the present invention provides serine protease variants, more specifically subtilisin variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants, more specifically subtilisin variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants, more specifically subtilisin variants.

Compositions and methods comprising serine protease variants

Variants ofsp. no. 707 alpha-amylase are provided that are produced more efficiently and thus more economically. Higher fermentation yields are achieved through introducing amino acid variations that promote solubility of the variant in a fermentation broth. Increased solubility allows more enzyme to remain in solution after expression in a host cell. This in turn increases the efficiency with which the expressed variant enzyme can be recovered from the fermentation broth.

Alpha-amylase variants

The present invention provides methods and compositions comprising at least one perhydrolase enzyme for cleaning and other applications. In some particularly preferred embodiments, the present invention provides methods and compositions for generation of peracids. The present invention finds particular use in applications involving cleaning, bleaching and disinfecting.

Perhydrolase

The present invention relates to modified variant Bowman Birk Protease Inhibitor proteins (BBPIs) that comprise peptides that bind target proteins, and that are further modified to have greater protease inhibitory activity and/or be produced at greater yields than the unmodified BBPIs. The invention encompasses polynucleotide constructs and expression vectors containing polynucleotide sequences that encode the modified variant BBPIs, the transformed host cells that express and produce the modified variant BBPIs, the modified variant BBPI proteins, the compositions comprising the modified variant BBPIs, and the methods for making and using the modified variant BBPIs in personal care.

Modified variant Bowman Birk protease inhibitors

The present invention provides methods and compositions comprising at least one perhydrolase enzyme for cleaning and other applications. In some embodiments, the present invention provides methods and compositions for generation of long chain peracids. Certain embodiments of the present invention find particular use in applications involving cleaning, bleaching and disinfecting.

Enzyme for the production of long chain peracid

Variants ofsp. no. 707 alpha amylase are provided that are produced more efficiently and thus more economically. Higher fermentation yields are achieved through introducing amino acid variations that promote solubility of the variant in a fermentation broth. Increased solubility allows more enzyme to remain in solution after expression in a host cell. This in turn increases the efficiency with which the expressed variant enzyme can be recovered from the fermentation broth.

Variants of an alpha-amylase with improved production levels in fermentation processes

Disclosed herein are compositions comprising an alpha-amylase enzyme obtained fromsp. no. 195, and methods of using the enzyme to clean surfaces and textiles. Also disclosed are variants of the enzyme with different signal sequences.

Modified variant Bowman Birk Protease Inhibitors

Modified variant bowman birk protease inhibitors

The present invention relates to compositions that comprise modified variant Bowman Birk Protease Inhibitor proteins (BBPIs). The modified variant BBPIs comprise peptides that bind target proteins, and that are further modified to have greater protease inhibitory activity and/or be produced at greater yields than the unmodified BBPIs. The invention encompasses the compositions comprising the modified variant BBPIs, and the methods for making and using the compositions in personal care.

Personal care compositions comprising modified variant Bowman Birk Protease Inhibitors

Growing community of inventors

Palo Alto, CA, United States of America

Neelam S Amin