Dionex Corporation

Neboisa Avdalovic

Christopher A Pohl

Kannan Srinivasan

John R Stillian

Roy D Rocklin

Victor Berber Barreto

James R Thayer

A method and apparatus for increasing the current efficiency of suppressor and suppress-like pretreatment devices is disclosed for the purpose of suppressing a high concentration of eluent without the detrimental effects of excess heat generation. The method and apparatus may be used in ion chromatography.

Current-efficient suppressors and method of use

A method of coating a solid support (e.g. a capillary or chromatography packing) to alter the properties of the support surface for separating components in a fluid stream. The method comprises (a) covalently binding a coupling agent (including functional groups capable of forming free radical sites under hydrogen abstraction conditions) to the support surface in a uniform layer, and (b) thereafter, contacting the bound coupling agent with a solution of preformed polymer comprising totally saturated carbon chain backbones including leaving groups, under hydrogen abstraction conditions of elevated temperature in the presence of a free radical catalyst to remove leaving groups from the carbon chains to form free radical carbon binding sites which covalently bond to the coupling agent layer and to crosslink at least some of the preformed polymer through the free radical carbon binding sites to form a dimensional polymer network coating on said solid support surface. Alternatively, the coating is applied directly to an organic solid support without an intermediate coupling agent.

Preformed polymer coating process and product

Apparatus and methods are provided for increasing the sensitivity of detection of ionic species separated by capillary electrophoresis. The apparatus includes capillary electrophoretic separating means, suppressor means and detector means.

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San Jose, CA, United States of America

Neboisa Avdalovic