Millikelvin Technologies LLC

Bruker Biospin Gmbh

Oxford Instruments Superconductivity Limited

Neal Kalechofsky

Avrum Belzer

Mirko I Hrovat

Melanie Rosay

Charles Monroe

James G Kempf

Matthew Hirsch

A carrier for a sample of highly polarized material includes a shell having a radially exterior surface and a radially interior surface, and a sample of highly polarized material interiorly adjacent to the radially interior surface. The shell may be substantially cylindrical, and may be constructed from a magnetic or non-magnetic material. The sample of highly polarized material may comprise a methyl rotor group material. The sample of highly polarized material may comprise pyruvic acid or an acetic acid. The sample of highly polarized material may be co-axial with the cylindrical shell. The sample of highly polarized material may be bonded or frozen to the radially interior surface of the shell. The carrier may further comprise a wad of material that forms a volume and contacts an axially proximate end of at least one of the shell or the sample.

Polarization sample geometry

A method of providing a material sample in a state favorable to retaining spin polarization includes cooling a material sample from a temperature above a freezing point of the material sample down to a second temperature below the freezing point of the material sample; maintaining the sample at about the second temperature for a period of about several hours; and reducing temperature of the material sample to a third temperature lower than the second temperature to provide the material sample in a state favorable to retaining spin polarization, where the steps of cooling, maintaining and reducing are performed in the absence of an adulterant material. The method of providing a sample of pyruvic acid in a state favorable to retaining spin polarization may include cooling the sample of pyruvic acid in the absence of an adulterant material from a temperature above a freezing point of the sample of pyruvic acid down to less than about 200 Kelvin to provide the sample.

Sample-preparation method to manipulate nuclear spin-relaxation times, including to facilitate ultralow temperature hyperpolarization

The present disclosure provides various methods and systems for performing magnetic resonance studies. In accordance with many embodiments, image or other information of interest is derived from super radiant pulses.

Techniques, systems and machine readable programs for magnetic resonance

The disclosure provides various methods and systems for providing hyperpolarized materials as well as the hyperpolarized materials so provided. In addition, methods of providing hyperpolarized materials, such as agents, to end users from a remote location are also provided.

Hyperpolarization methods, systems and compositions

The present disclosure provides various methods and systems for manufacture, transport and delivery of material including highly polarized nuclei that is in a hyperpolarized state.

Systems and methods for producing hyperpolarized materials and mixtures thereof

The present invention relates to a method of hyperpolarizing a gas sample. The method cryogenically forming a solidified gas structure from the sample gas, the solidified gas structure being surrounded by He. A magnetic field is then to the solidified gas structure and the He to thereby polarize the solidified gas structure, before the He is removed to thereby leave a solidified gas structure of hyperpolarized sample gas.

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Stow, MA, United States of America

Neal Kalechofsky