Muffin Incorporated

Med Institute Incorporated

Cook Incorporated

Cook Medical Technologies LLC

Other

Cook Biotech, Inc.

Purdue Research Foundation

Medical Engineering and Development Institute, Inc.

Cook Pacemaker Corporation

National Institutes of Health, a Component of the US Dept. of Health & Human Services

Wilson-cook Medical Incorporated

Cook Urological, Inc.

National Institutes of Health, Dhhs

Cook Myosite Incorporated

William Cook Europe Aps

Neal E Fearnot

Brian L Bates

Anthony O Ragheb

William D Voorhees, Iii

Thomas G Kozma

Peter S McKinnis

Sarah Robbins

Yun Zhou

William John Havel

Michael C Hiles

Thomas A Osborne

Leslie A Geddes

James D Purdy

John Crowder Sigmon, Jr

Shaun D Gittard

Gregory James Hardy

Alan R Leewood

William A Cook

Chad E Johnson

Joshua Frye Krieger

Michael P DeBruyne

Richard B Sisken

Jichao Sun

Blayne A Roeder

Frank J Fischer, Jr

Louis B Goode

Frederick J Shipko

Kasper Klausen

Ram H Paul, Jr

Umesh H Patel

Steven Charlebois

Palle Munk Hansen

Charles Leland Baxter

Joe D Bourland

Toby Rogers

Mark W Bleyer

Brian C Case

Vihar C Surti

Stephen Francis Badylak

Edward D Pingleton

Sean Chambers

Scott E Boatman

Joseph P Lane

F Joseph Obermiller

Robert J Lederman

Jeremy T Newkirk

Marc C Buhrmester

John A DeFord

Brian D Choules

William J Bourdeau

Ronald Jankowski

Marc G Apple

Thomas Payne

Joseph M Stewart, Iv

Christopher J Moran

Rita Hadley

Gary Bradford Shirley

Joseph W Roberts

Jeffrey A Miller

Lal Ninan

J Alexander Marchosky

James R Randolph

Jason A Mead

Kanishka Ratnayaka

Coy M Herald

Clinton D Bahler

Robert L Lederman

Jose A Marchosky

Gabriel Converse

Anthony H Gershlick

Dale T Berry

Jimmy L Taylor, Jr

Ralph V Clayman

Michael C Hoffa

Krishna Rama Narayanan

Patrick H Ruane

Gregory A Frankland

Gary Neff

David R Lessard

Charles F Babbs

James Thomas Jones

William L Johnson

Gary L Butler

Donald A Stevens

John C Sigmon

Jeremy Metz

Niraj Ramachandran

Waleska Perez-Segarra

Kyle D Amick

Melvin Kem Hawkins

Oiva A Paavola

Kem Hawkins

Joseph F Ely

Gregory D Elliott

Timothy A Chuter

Jerry L Wessale

Kevin S Heggs

Andrew J Kaucher

Michelle Martinez

Jesper Thyregod

Differential pressure material processing systems, apparatus, methods, and products are described. An example embodiment of a differential pressure material processing system includes a tank, a holding member, and a sheet of tissue disposed within the holding member. The holding member defines a first holding member chamber and a second holding member chamber. The first holding member chamber has a first pressure when a fluid is disposed within the first holding member chamber. The second holding member chamber has a second pressure when a fluid is disposed within the second holding member chamber. The second pressure is different than the first pressure.

Differential pressure material processing systems, apparatus, methods, and products

Described are methods and systems and system components useful for percutaneously delivering or retrieving vascular implant devices, such as filters, utilizing intravenous ultrasound (IVUS) imaging alone or in combination with external (e.g. transabdominal) ultrasound or other imaging technology. Implants deliverable by such systems, such as vena cava or other vascular filters, can have two or more echogenic markers spaced at such a distance that they are separately discernible by IVUS and/or external ultrasound imaging.

Percutaneous, ultrasound-guided introduction of medical devices

Material processing apparatus, systems, methods, and products are described. An example of a material processing apparatus includes a holding member, a base, a tensioning member, an actuator, and a first inner member. The holding member defines a holding member passageway. The base is attached to the holding member. The tensioning member is partially disposed within the holding member passageway. The tensioning member defines a tensioning member passageway. The tensioning member is moveable relative to the holding member between a first position and a second position. The actuator is attached to the tensioning member and is moveable in a first direction and a second direction. Movement of the actuator results in movement of the tensioning member between its first position and second position. The first inner member is adapted to be disposed within the tensioning member passageway.

Cell tissue processing apparatus, systems, methods, and products

Among other things, there are disclosed embodiments of belts or bands that can be used in treatments for tricuspid valve regurgitation. In some embodiments, such belts may be heat-set in a particular configuration to effectively decrease tricuspid annulus when deployed around the atrioventricular groove. Embodiments include one or more tensioning sutures for applying cinching or tightening to belts when deployed, and structure for effectively distributing force during such tightening. Embodiments of tensioning members, protective members, and devices and methods for open-surgical placement (e.g. around a heart for annuloplasty) are also disclosed.

Systems and methods for applying pressure to a bodily organ

Example access devices, treatment devices, and kits useful in performing treatment under magnetic resonance imaging and related methods are described. An example access device includes an elongate tubular member formed of an MRI compatible material and moveable between a first, unexpanded configuration and a second, expanded configuration. The elongate tubular member has a central lengthwise axis, a proximal end, a distal end, an axial length, and a main body that defines a circumferential wall, a lumen, a proximal opening, a distal opening, and a main body opening. The main body opening is arranged in a spiral relative to the lengthwise axis and extends circumferentially along the circumferential wall. The main body opening extends along the entire axial length of the elongate tubular member from the proximal end to the distal end.

Access devices, treatment devices, and kits useful for performing treatment under magnetic resonance imaging and related methods

Storage devices, loading devices, delivery systems, kits, and associated methods for implantable medical devices are described. An example embodiment of a storage device includes a storage member, a first cap, and a second cap. The storage member has a first end, a second end, and a main body that defines a first opening, a second opening, a passageway, a separating wall, and a plurality of holes. The passageway has a first portion and a second portion. The first portion extends from the first end of the storage member to the separating wall and the second portion extends from the second end of the storage member to the separating wall. Each hole of the plurality of holes extends through the separating wall and provides access between the first portion and the second portion. Each of the first and second caps is releasably attached to the storage member.

Storage devices, loading devices, delivery systems, kits, and associated methods

Described are methods, cell growth substrates, and devices that are useful in preparing cell-containing graft materials for administration to patients. Tubular passages can be defined in cell growth substrates to promote distribution of cells into the substrates. Also described are methods and devices for preparing cell-seeded graft compositions, methods and devices for preconditioning cell growth substrates prior to application of cells, and cell seeded grafts having novel substrates, and uses thereof.

Methods, substrates, and systems useful for cell seeding of medical grafts

Among other things, there is disclosed structure and methods for maintaining access to a location in the body while reducing or eliminating the potential for pulling an access device (e.g. a catheter) back through an opening. An introducer sheath includes a distal indented portion and a balloon, so that once placed in a desired location through tissue, the balloon can be inflated to anchor the sheath against retraction. In particular embodiments, structure and methods for accessing the pericardial cavity via the right atrial appendage are shown.

Vascular anchoring introducer sheath

There are shown and described embodiments of a closure device for closing holes in tissue, for example in the right atrial appendage. The closure device in particular embodiments includes first and second mesh closure members and a tether or stem connecting them. Embodiments of a delivery device for the closure device are also described.

Closing device for tissue openings

Among other things, there are shown embodiments of locking mechanisms for holding sutures in tension. Such devices may be used with implants that use or require sutures, and are easily locked remotely. In particular embodiments, a lock includes a housing member, a pin member at least partially within the housing member, and a spring biasing the pin member into the housing member. The pin member includes a gripping portion, and has a retracted condition and a locked condition. When retracted, a suture can move through the housing member and around the gripping portion of the pin member. When locked, the gripping portion of the pin member engages the suture and presses it against the interior of the housing member.

Suture lock device

Described are embodiments of a multilaminate or multiple layer implantable surgical graft with an illustrative graft comprising a remodelable collagenous sheet material, the graft including one or more interweaving members to stitch together the graft to help prevent the layers from delaminating or separating during handling and the initial stages of remodeling. The interweaving members may comprise lines of suture, thread, individual stitches, strips of material, etc. that are woven through the layers of biomaterial in a desired pattern. In one embodiment, the interweaving members comprise a pharmacologically active substance, such as a drug, growth factors, etc. to elicit a desired biological response in the host tissue. In another embodiment, the graft further comprises a reinforcing material, such as a synthetic mesh, within the layers of remodelable biomaterial and stitched together by one or more interweaving members.

Quilted implantable graft

Disclosed are embodiments of devices and methods for imaging the inside of a body part, such as a blood vessel. In particular embodiments, a catheter has a chamber within which is a transducer. A wire guide channel extends throughout the length of the catheter. The transducer is rotatable about the wire guide channel and the transducer is driven by a cable or other device that is connected to a motor which is located outside the catheter. In one form, a torque cable connects the transducer to the motor. In other embodiments, a pusher piece having a plurality of lumens is positioned in the catheter. Each of the lumens is sized to receive a cable, wire, and/or flushing fluid. The lumens maintain the orientation and separation of the cables, wires, and/or to flushing fluid.

Over-the-wire ultrasound system with torque-cable driven rotary transducer

Described are medical products, methods, and cryogenic bags or other containers suitable for storing and/or transporting and/or processing cellular compositions and other related materials. In certain aspects, the contents of such cryogenic bags may be warmed, mixed, and applied to a patient. Medical products described herein find particular use in treating diseased and/or damaged tissue such as in wound repair and/or bone repair. Related methods of manufacture are also described.

Compartmented cryopreservation container and uses thereof

Growing community of inventors

Lafayette, IN, United States of America

Neal E Fearnot