The University of Texas System

Navid Ghorashian

Adela Ben-Yakar

Sertan Kutal Gökçe

William Neil Everett

Evan Hegarty

Sudip Mondal

Christopher Martin

Frederic Bourgeois

Sam Xun Guo

Sertan Kutal Gokce

A microfluidic device capable of trapping contents in a manner suitable for high-throughput imaging is described herein. The microfluidic device may include one or more trapping devices, with each trapping device having a plurality of trapping channels. The trapping channels may be configured to receive contents via an inlet channel that connects a sample reservoir to the trapping channels via fluid communication. The trapping channels are shaped such that contents within the trapping channels are positioned for optimal imaging purposes. The trapping channels are also connect to at least one exit channel via fluid communication. The fluid, and contents within the fluid, may be controlled via hydraulic pressure.

High-throughput imaging platform

Microfluidic devices for the rapid and automated processing of sample populations are provided. Described are multiplexer microfluidic devices configured to serially deliver a plurality of distinct sample populations to a sample processing element rapidly and automatically, without cross-contaminating the distinct sample populations. Also provided are microfluidic sample processing elements that can be used to rapidly and automatically manipulate and/or interrogate members of a sample population. The microfluidic devices can be used to improve the throughput and quality of experiments involving model organisms, such as

Microfluidic devices for the rapid and automated processing of sample populations

Growing community of inventors

Sunnyvale, CA, United States of America

Navid Ghorashian