Cima Labs Inc.

Navayanarao Madamala

Fred Wehling

Steve Schuehle

A tableting aid including magnesium carbonate and an oil adsorbed thereon provides useful lubricating and disintegration properties. A free-flowing particulate flavoring additive including magnesium carbonate and a flavor oil adsorbed thereon, is also described.

Magnesium carbonate and oil tableting aid and flavoring additive

The present invention relates to oral effervescent dosage forms for the administrations of an intended ingredient to children, and processes for their administration.

Pediatric effervescent dosage form

A pharmaceutical dosage form incorporates microparticles which are susceptible to rupture upon chewing or which are adapted to provide substantially immediate release of the pharmaceutical ingredient contained in the microparticles. These microparticles are provided in a tablet with an effervescent disintegration agent. When the tablet is taken orally, the effervescent disintegration agent aids in rapid dissolution of the tablet and hence permits release of the microparticles, and swallowing of the microparticles, before the pharmaceutical ingredient is released from the microparticles. The system therefore provides particularly effective taste masking.

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Plymouth, MN, United States of America

Navayanarao Madamala