Daiichi Sankyo Company, Limited

Natsumi Nishihama

Shinji Tanaka

Keiji Saito

Osamu Iwamoto

Katsuyoshi Nakajima

Nobuya Kurikawa

Wataru Saitoh

Momoko Ogitani

Yasuyuki Ogawa

Kazumasa Aoki

Toru Taniguchi

Satoshi Shibuya

Kaori Ito

Eriko Kioi

Tsuyoshi Mikkaichi

Nobuyuki Ohkawa

Hiroyuki Tsuruoka

Tsuyoshi Soneda

Junya Kawai

Yuma Umezaki

Tomohiro Honda

An object of the present invention is to provide a compound having an anti-inflammatory activity or a pharmacologically acceptable salt thereof. The solution of the present invention is a compound of general formula (1) or a pharmacologically acceptable salt thereof. wherein the symbols in the formula are defined below: R: e.g., a C1-C6 alkyl group; R: a C1-C6 alkyl group; A: e.g., an oxygen atom; and R: e.g., a C1-C6 alkyl group.

Griseofulvin compound

An object of the present invention is to provide a compound that has a specific chemical structure having an activation effect on SIRT6 and is useful as an active component for preventing and treating inflammatory diseases, and the present invention relates to a compound represented by Formula (1) or a pharmaceutically acceptable salt thereof,

Urea compound having substituent

An object of the present invention is to provide a compound having an anti-inflammatory activity or a pharmacologically acceptable salt thereof. The solution of the present invention is a compound of general formula (1) or a pharmacologically acceptable salt thereof. wherein the symbols in the formula are defined below:R: e.g., a C1-C6 alkyl group; R: a C1-C6 alkyl group;A: e.g., an oxygen atom; and R: e.g., a C1-C6 alkyl group.

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Yokohama, Japan

Natsumi Nishihama