Terumo Bct Biotechnologies, LLC

Other

Nathaniel T Johnson

Kestas P Parakininkas

Dennis J Hlavinka

Kirk L Weimer

Dennis A Bridges

Rylan A Summit

Alexander Du Nguyen

Margaret V Kwiat

Eric T Hansen

Michael Lawrence Glover

Provided is a multi-part lyophilization container for lyophilizing a fluid, storing the lyophilizate, reconstituting the lyophilizate, and infusing the reconstituted lyophilizate into a patient, including a method of using same. The container includes a front surface, a back surface, a non-breathable section including a port region, a breathable section including a breathable membrane, and a peelable region including a peelable seal encompassing a boundary between the non-breathable section and the breathable section. The method includes inputting a fluid into a non-breathable section of the container, freezing the fluid, applying, in a lyophilization chamber, vacuum pressure, opening the peelable seal using a pressure differential, applying heat energy, sublimating the fluid and creating a temporary occlusion in a peelable region of the container.

Multi-part lyophilization container and method of use

Provided is a gas fill fixture for use in lyophilization, a related system and method. The gas fill fixture includes a chassis, fill indicator and a lid, such that the chassis and lid together form a cavity for receiving a flexible lyophilization container. The system includes a lyophilization container, a lyophilizer and a gas fill fixture incorporating a chassis, a fill indicator and a lid. The method includes process steps for using the system to lyophilize a fluid.

Lyophilization container fill fixture, system and method of use

Provided is a loading tray assembly for housing a lyophilization container and a related system and method. The loading tray assembly includes a chassis including a contact void configured to facilitate direct contact between the attached lyophilization container and a lyophilizer shelf. The method includes securing a multi-part lyophilization container including a peelable seal on a lyophilization loading tray assembly, inputting a liquid into a non-breathable section of the lyophilization container, loading the tray assembly into a lyophilizer, freezing the liquid, applying heat energy and a vacuum, the vacuum causing an opening of the peelable seal and occluding the lyophilization container to isolate the frozen liquid.

Lyophilization loading tray assembly and system

An ice melting assembly for inhibiting ice and snow from collecting in a wheel well includes a liner that is mounted in a wheel well of a vehicle. A heating element is positioned within the liner and the heating element is in thermal communication with the liner. A control is provided and the control is selectively manipulated. The control is electrically coupled to the heating element to turn the heating element on and off.

Ice melting assembly

Growing community of inventors

Highlands Ranch, CO, United States of America

Nathaniel T Johnson