Life Technologies Corporation

454 Life Sciences Corporation

Nathan Kane

Mark T Reed

Hideji Tajima

Earl M Zergiebel

David Marran

Tetsuya Ueda

Joseph Podhasky

Shuichi Kobayashi

A system includes a pipetting system including a 3-axis gantry; a sled mechanism to select a magnetic comb from a set of magnetic combs; a fluorometer; and a set of receptacles to receive welled plates. A method for purifying nucleic acids includes applying a sample to a well of a multi-well plate, selecting a magnetic comb from a set of magnetic combs disposed on a gantry system, collecting magnetic beads using the magnetic comb, collecting nucleic acid using the magnetic beads, and eluting the nucleic acid from the beads.

System and method for polynucleotide purification

Multicomponent cartridge

A pipetting system includes a rail; a carriage to engage the rail, the carriage movable relative to the rail substantially along a first axis; a pipette pump slidably engaged with the carriage, the pipette pump slidable relative to the carriage substantially along the first axis; and a sensor to detect movement of the pipette pump relative to the carriage.

Pipette system

An embodiment of a device for automatically executing a process of generating an emulsion containing nucleic acids, amplifying the nucleic acids in the emulsion, breaking the emulsion, and separating and purifying said amplified nucleic acids, is described that comprises an emulsion generation unit for sealing beads to which nucleic acids are bound in a water-in-oil type emulsion; a nucleic acid amplification unit provided with a reaction vessel for amplifying said nucleic acids and a heating and cooling part for heating and cooling the reaction vessel; an emulsion breaking unit for breaking the emulsion after nucleic acid amplification; and a nucleic acid purification unit for recovering said amplified nucleic acids from said emulsion breaking unit.

System and method for automated nucleic acid amplification

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Guilford, CT, United States of America

Nathan Kane