Biora Therapeutics, Inc.

Endra Life Sciences Inc.

Cedars-sinai Medical Center

Progenity, Inc.

Perceptive Technologies, Inc.

Baker Group, Llp

Jones, Ryan Elliott

Drlik, Mark Sasha

Nguyen, Tuyen

Niknia, Iman

Muller, Nathan John

Abercombie, Stuart Robert

Salt, Nicholas Mark

Stevens, Nia Eleri

Jones, Mitchell Lawrence

Nathan John Muller

Mark Sasha Drlik

Mitchell Lawrence Jones

Christopher Loren Wahl

Iman Niknia

Tuyen Nguyen

Jeffrey A Shimizu

Nelson Quintana

Edward Mudge

Nicholas Mark Salt

Nia Eleri Stevens

Stuart Robert Abercrombie

Christopher Ian Bunce

Nigel Anthony Syrotuck

Michael M Thornton

Nicholas David Allan

Kevin Howe

Scott Patrick Belanger

Ryan Elliott Jones

Martin Leandro Par

Amy L Sitzler

Richard Moss

Victor Motov

Dmitry V Vasilenko

Laura Karik

Timothy Sang-Ook Park

Christine Park

Pejman Rahimian

Mark Pimentel

James Jackson

Michael John Baker

Aaron Olafur Laurence Philippsen

Ali Rezaie

Paul Charlebois

Kapil Gupta

Kenneth Maccallum

Christian Terry Proch McMechan

Christopher John Ciriello

Brian Edward King

Martin Juergen Kellinghusen

Kristofor Dyck Dolberg

Sudeshna Dutta

Gene Alan Wey

Andrew Carlos Garland

Kevin David Howe

An automated dental drill includes an end effector, including a dental tool for disposition at least partially in a patient's mouth and to perform an operation on a tooth. A tooth clamp releasably rigidly attaches to at least one tooth. A drive assembly is controlled by a processor and positions the end effector with a first at least three degrees of freedom, relative to the tooth clamp. The drive assembly remains outside the patient's mouth. A clamp connector connects the tooth clamp to the drive assembly. With the tooth clamp coupled to the drive assembly and the tooth clamp attached to the at least one tooth, position and orientation of the drive assembly remain fixed, relative to the at least one tooth. A passive cantilever arm, mechanically coupled between a support structure and the drive assembly, has a second at least three degrees of freedom and supports the drive assembly.

Automated dental drill

Systems and methods have been developed for implementation of a breath testing system for convenient sampling of intestinal gases exhaled from a patient's breath. This may include a system with a manifold that includes thermal regulation components, for instance thermistors and resistive heating elements, which maintain the temperature of the gases above the body temperature of the patient. In some examples, the system will determine an indication of whether a patient has SIBO by adjusting a change in exhaled hydrogen concentration by a methane level exhaled by a patient.

Breath gas analysis

Ingestible devices can directly deliver therapeutic agents to desired tissue(s) of the GI tract of a subject, such as the submucosa, the mucosa, and/or the mucus layer of the GI tract, and methods of using the same. The ingestible devices can deliver therapeutic agents in a safe, effective, and reliable manner. The disclosure also provides pharmaceutical compositions for use in methods of treating a disease or condition in a subject in need thereof.

Ingestible device for delivery of therapeutic agent to the gastrointestinal tract

Ingestible devices capable of delivering a dispensable substance, such as, for example, a therapeutic agent, as well as related components, systems and methods, are disclosed. A removably attachable storage reservoir configured to be used with an ingestible device and capable of storing dispensable substance, such as, for example, a therapeutic agent, as well as related components, systems and methods, are also disclosed.

Ingestible device for delivery of a dispensable substance

A method of treating a disease or condition in a subject in need thereof is disclosed. The method comprising: trans-epithelially administering a dispensable substance to the gastrointestinal (GI) tract of the subject by orally administering an ingestible device comprising the dispensable substance to the subject. The ingestible device is configured for trans-epithelial delivery of the dispensable substance to the GI tract of the subject and the dispensable substance comprises a pharmaceutical formulation comprising a therapeutically effective amount of a glucagon receptor agonist or a glucagon-like peptide-1 (GLP-1) receptor agonist. The ingestible device releases the dispensable substance as at least one jet to a desired location of the GI tract of the subject.

Methods and systems for a catheter access port cleaning, disinfection or sterilization device are disclosed. The catheter access port cleaning, disinfection or sterilization device may comprise, a first housing having a power source and control circuit; a second housing shaped to mate with a catheter and having a first ultra-violet light source mounted therein, the first housing wired to the second housing to power the light source. When activated, the ultra-violet light source emits ultra-violet radiation that is transmitted from the second housing to the catheter attached to a patient. In this way, the device provides an efficient system for cleaning, disinfecting or sterilizing an access port in the second housing while reducing patient infections.

Device and method for sterilizing a catheter system

An ingestible device, includes a storage reservoir configured to store a dispensable substance and a pressurized chamber configured so that, when a restraining force is removed from the pressurized chamber, the dispensable substance exits the ingestible device via openings in the ingestible device.

Thermoacoustic imaging probe

Thermoacoustic imaging probe with outdents

Growing community of inventors

Victoria, Canada

Nathan John Muller