The Procter Gamble Company

Pepsico, Inc.

Ethicon, Gmbh

Cilag International Gmbh

Gyroscope Therapeutics Limited

Genentech, Inc.

The Procter & Gamble Plaza

Orbit Biomedical Limited

Novasurg Innovations, LLC

Nathan Daniel Grubbs

Andrew William Franckhauser

Scott Edward Smith

Stefano Bartolucci

Daniel W Price

Michel Bruehwiler

Brendan J Oberkircher

Michael F Keane

Advait Rasik Bhat

Isaac John Khan

Bruno Telesca

Girish Nilkanth Deshpande

Saeed Sokhanvar

Benjamin L Ko

Daniel J Yasevac

Daniel James Prenger

Maximiliano Rodriguez

Ryan Alan Klenke

Leah R Soffer

Christopher D Riemann

Benjamin Joseph Tantanella

Kerry Lloyd Weaver

Robert Earl Magness

Nathaniel David Thulin

Cory G Kimball

David A Witt

William Eugene Clem

Paul Owen Nutley

Laura Boehm

Collin James Loch

Frederick E Shelton, IV

Ryan M Asher

Benjamin D Dickerson

Ashvani K Madan

Kristen G Denzinger

Douglas Bruce Zeik

Matthew Corey Cataudella

Justin Alan Ellsworth

Mitchell Edwin Messenger

Alexander David Warning

Lei Zhao

Jason L Harris

Chester O Baxter, Iii

Christopher J Hess

Mark D Overmyer

Michael J Stokes

Robert L Koch, Jr

Adam David Hensel

William Mercer Benson

Jeffrey L Savage

Todd Mitchell Day

Christopher Luke Leonard

Vincenzo Barbato

James Alexander Morley

John Martin Shields

Syed M Hussain

Paul O Nutley

Laura A Boehm

Advait Bhat

Iii Chester O Baxter

Jr Robert L Koch

Collin J Loch

An apparatus for delivering therapeutic agent to an eye comprises a body, a cannula, a hollow needle, and an actuation assembly. The cannula extends distally from the body and is sized and configured to be insertable between a choroid and a sclera of a patient's eye. The actuation assembly is operable to actuate the needle relative to the cannula to thereby drive a distal portion of the needle along an exit axis that is obliquely oriented relative to the longitudinal axis of the cannula. The cannula may be inserted through a sclerotomy incision to position a distal end of the cannula at a posterior region of the eye, between the choroid and sclera. The needle may be advanced through the choroid to deliver the therapeutic agent adjacent to the potential space between the neurosensory retina and the retinal pigment epithelium layer, adjacent to the area of geographic atrophy.

Method and apparatus for suprachoroidal administration of therapeutic agent

A surgical apparatus comprises a transducer assembly and a shaft assembly. The transducer assembly is operable to convert electrical power into ultrasonic vibrations. The shaft assembly comprises an ultrasonic waveguide, a sheath, a shroud, and a torque transfer assembly. The waveguide is configured to couple with the transducer assembly. The waveguide is disposed within the sheath. The sheath extends through the shroud. The torque transfer assembly is contained within the shroud. The torque transfer assembly is configured to transfer a predetermined range of torque from the shroud to the waveguide to thereby couple the waveguide with the transducer assembly. The torque transfer assembly is further configured to prevent transfer of torque from the shroud to the waveguide beyond an upper limit of the predetermined range.

Methods and features for coupling ultrasonic surgical instrument components together

Method and apparatus for subretinal administration of therapeutic agent

A dispensing device for dispensing a foamable product. The dispensing device comprises a dispensing channel (). The dispensing channel has: an inlet () for communicating with a valve-element () of a container () containing the foamable product; and an outlet () for dispensing the foamable product. The dispensing channel () further comprises a variable-volume cavity () at the outlet. The variable-volume cavity () is defined at least partly by a first component () and a second component () that is separate from and rigidly movably with respect to the first component to vary the volume of the variable-volume cavity () between a first configuration and a second configuration. In the first configuration, the variable-volume cavity () has a first volume and the outlet () is closed. In the second configuration, the variable-volume cavity has a second volume and the outlet () is open. The second volume is greater than the first volume.

Dispensing device suitable for a foamable product

Dispensing packages for a spreadable personal care product and its respective methods for dispensing a spreadable personal care product. The dispensing package comprises a reusable dispenser, a replaceable cartridge and optionally a top cap. The reusable dispenser comprises a tubular body and a telescopic actuator. The reusable dispenser comprises a locking ring removably engaged with the tubular body of the reusable dispenser to secure the replaceable cartridge within the tubular body of the reusable dispenser.

Sustainable dispensing package having a locking ring

A threaded valve for an aerosol container. The threaded valve comprises a housing, a moving assembly disposed in the housing, threads suitable for threadable onward attachment onto a complementary neck of an outer container for an aerosol dispenser and a plurality of pawls and/or ratchets disposed on and extending from the housing. The pawls and/or ratchets allow onward rotation of the valve onto the complementary neck and impeding rotational detachment of the valve in a reverse direction.

Threaded valve having an anti-removal feature for use in an aerosol dispenser

A product dispenser with a reservoir adapted for a product and a cap. The reservoir has a protrusion and a piston engaging mechanism. The cap has a pipette, a piston configured to move to create a suction to draw the product through a lower end orifice of the pipette, a housing for the piston, a corresponding engaging mechanism, a button configured to dispense the product, and a chamber configured to change its volume depending on the movement of the piston and the movement of the button.

Dispenser for viscous products

A dispensing package for a spreadable personal care product and its respective methods for dispensing the product. The dispensing package comprises a reusable dispenser, a replaceable cartridge and optionally a top cap. The reusable dispenser comprises a tubular body and a telescopic actuator. The telescopic actuator comprises a hand wheel, a leading screw, a tubular screw and an elevator. The replaceable cartridge comprises a push plate. The telescopic actuator is able to engage with the push plate of the replaceable cartridge to deliver the personal care product such that a top surface of the elevator telescopes with a bottom surface of the push plate of the replaceable cartridge.

Sustainable dispensing package having a telescopic actuator

An apparatus for operating on tissue includes a body, a shaft assembly, and an end effector. The shaft assembly extends distally from the body and includes an acoustic waveguide. The waveguide is configured to acoustically couple with an ultrasonic transducer. The end effector includes an ultrasonic blade, a clamp arm, and a clamp pad. The blade is in acoustic communication with the waveguide. The clamp arm is configured to pivot about a first pivot point toward and away from the ultrasonic blade and includes a coupling feature. The clamp pad is selectively attachable to the blade to acoustically isolate the clamp arm from the ultrasonic blade. The coupling feature of the clamp arm is configured to provide a snap fit between the clamp pad and the clamp arm and thereby permit manipulation of the clamp pad for removal of the clamp pad from the clamp arm.

Ultrasonic surgical instrument clamp arm with snap-on clamp pad

An outer container for an aerosol dispenser. The outer container has a closed end bottom and a longitudinally opposed open, open neck. A complementary valve can be received in the neck. A cap overlays the valve and engages the outer container, valve, or both, to prevent removal of the valve. The cap may have threads, ratchets/pawls, splines, spikes, bayonet fitting or combination thereof to engage the valve or outer container.

Aerosol dispenser having a cap to prevent valve removal

A multi-composition product dispenser capable of concurrently dispensing at least a first and second composition is provided.

Multi-composition product dispenser

A preform suitable for blow molding into for an outer container usable for a pressurized aerosol dispenser. The preform has a longitudinal axis and a closed end bottom, an open neck. The neck has threads for accepting a valve having complementary threads. At least one pawl or ratchet is operatively juxtaposed with the periphery of the preform. The at least one pawl or ratchet allows onward rotation of the complementary valve in an onward direction, and prevents detachment of the valve in a reverse rotation direction. Any such preform can be blow molded into a corresponding outer container, and any such outer container can be blow molded from a corresponding preform.

Preform with valve anti-removal feature

An aerosol container for an aerosol dispenser. The aerosol container has an outer container. The outer container has a closed end bottom and a longitudinally opposed threaded open neck. The open neck has one or more pawls or ratchets disposed near the neck. The pawls or ratchets allow a complementary valve to be threaded onto the neck. The valve has complementary ratchets or pawls. The ratchet and pawl combination co-acts to impede or even prevent reverse rotation and subsequent removal of the valve. The outer container may be made from a preform having the ratchets and/or pawls integrally molded as part of the injection molding process. A valve having a housing may have ratchets and or pawls integrally molded as part of the injection molding process.

Aerosol dispenser with valve anti-removal feature

Growing community of inventors

Cincinnati, OH, United States of America

Nathan Daniel Grubbs