Université Grenoble Alpes

Commissariat &#xc0; L'&#xc9;nergie Atomique Et Aux &#xc9;nergies Alternatives

Commissariat a L'energie Atomique

Nathalie Picollet-D'Hahan

Donald Keith Martin

Patrick Chaton

Stephane Getin

A microfluidic cell culture chip which contains a central module comprising a central unit, which contains a support consisting of a non-resorbable membrane, a 3D nanostructured porous membrane, comprising at least one protuberance, and the 3D nanostructured porous membrane and that at least one protuberance being composed of materials suitable for the culture of two distinct cell types; a base, and the central unit being integrated in the base, and forming a whole with the base.

Cell co-culture chip and process for the production thereof

An in vitro method for diagnosing a urological cancer comprising the comparison of a secretome of isolated cells from a urine sample from a patient to be diagnosed with respect: either to a reference secretome obtained from secretions of healthy isolated cells from a urine sample from a healthy person, or to a reference secretome obtained from secretions of healthy cells which are derivatives of standard cell line cultures, characteristic of a determined urological organ, the secretome and the reference secretome being constituted of all the components forming the respective secretions thereof.

Method for diagnosing genitourinary cancers

A method for controlling directly and in real time positioning of a biological element on a zone of a support, in which the biological element is labeled with a tracer that emits a light radiation and the zone of the support is located in a layer of a material capable of trapping the light radiation. The biological element is positioned on the zone of the support. The intensity of the light radiation trapped in the layer is measured. The positioning of the biological element is determined by comparing the intensity thus measured with at least one reference value. The above operations can be carried out successively or simultaneously. A device can apply the method to the positioning of one or more biological elements on one or more zones of a support.

Growing community of inventors

La Ferriere, France

Nathalie Picollet-D'Hahan