Merial Limited

Boehringer Ingelheim Animal Health USA Inc.

Natalya Shub

Mark Soll

James Pate

Mark D Soll

Loic Patrick Le Hir De Fallois

Philip Reid Timmons

Joseph K Rosentel, Jr

Monica Tejwani-Motwani

Carol Belansky

Luiz Gustavo Cramer

Albert Boeckh

Patrice Wurtz

Krishan Kumar

Robert P Waranis

Mark David Soll

This invention relates to topical compositions for combating ectoparasites and endoparasites in animals, comprising at least one isoxazoline active agent and a pharmaceutically acceptable carrier, optionally in combination with one or more additional active agents. This invention also provides for an improved methods for eradicating, controlling, and preventing parasite infections and infestations in an animal comprising administering the compositions of the invention to the animal in need thereof.

Parasiticidal compositions comprising an isoxazoline active agent, methods and uses thereof

The invention provides for spot-on formulations comprising fipronil in a high concentration for the treatment or prophylaxis of parasites of mammals and birds, and in particular, cats, dogs, horses, chickens, sheep and cattle with the aim of ridding these animals of all the parasites commonly encountered by birds and mammals. The invention also provides for effective and lasting destruction of ectoparasites, such as fleas, ticks, itch mites and lice, and of endoparasites, nematodes, such as filariae, and roundworms of the digestive tract of animals and humans.

Parasiticidal compositions comprising fipronil at high concentrations

The invention is a pour-on antiparasitic formulation having superior water resistant properties. The pour-on formulation utilizes one or more polymers (water insoluble with or without water soluble) in the range of about 5 to about 40% w/w, one or more solvents in the range of about 50 to about 94% w/w, with or without additive (e.g., isopropanol or ethanol) in the range of about 5 to about 30% w/w, and optionally a plasticizer in the range of about 0.5 to about 25% w/w. The pour-on antiparasitic formulation features limited spreading when applied to animals (cattle, sheep, dogs and the like). The pour-on antiparasitic formulation further partially evaporates, leaving a water resistant polymer matrix that diffuses at least one active ingredient to the animal's skin.

Topical delivery formulation

This invention relates to compositions for combating parasites in animals, comprising 1-arylpyrazole compounds alone or in combination with formamidine compounds. This invention also provides for an improved methods for eradicating, controlling, and preventing parasite infestation in an animal comprising administering the compositions of the invention to the animal in need thereof.

Compositions comprising an aryl pyrazole and/or a formamidine, methods and uses thereof

Provided is a novel ivermectin derivative and compositions for the treatment or prophylaxis of parasite infestations in mammals or birds which comprise: 

Compositions comprising C-13 alkoxyether macrolide compounds and phenylpyrazole compounds

This invention provides for inter alia, topical anthelmintic formulations which comprise a pharmaceutically active combination consisting of at least one macrocyclic compound and at least one compound selected from the group consisting of praziquantel, morantel and pyrantel, which are dissolved in a non-aqueous solvent or solvent mixture and optionally a thickening agent.

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Allentown, PA, United States of America

Natalya Shub