Cancer Research Technology Limited

University of Southampton

Icon Genetics Gmbh

Cancer Research Ventures Limited

Natalia Savelyeva

Freda Stevenson

Yuri Gleba

Victor Klimyuk

Frank Thieme

Romy Kandzia

Franziska Jarczowski

Anja Nickstadt

Duc Bui-Minh

Freda K Stevenson

Warayut Chotprakaikiat

Protein conjugate comprising a protein antigen for generating an immune response against the HER2/neu protein and an immunogenic carrier covalently bonded to said protein antigen, wherein said protein antigen

HER2/Neu cancer vaccine

A nucleic acid construct is provided for delivery into living cells in vivo for inducing an immune response in a patient to an antigen; the construct directing the expression of a fusion protein, said fusion protein comprising said antigen and an adjuvant sequence derived from a plant viral coat protein. Methods for making constructs and methods of using such constructs for the treatment of infectious disease, cancer and B cell malignancy, are provided.

Materials and methods relating to fusion proteins for inducing an immune response

A nucleic acid construct is provided for delivery into living cells in vivo for inducing an immune response in a patient to an antigen; the construct directing the expression of a fusion protein, said fusion protein comprising said antigen and an adjuvant sequence derived from a plant viral coat protein. Methods for making such constructs, and methods of using such constructs for the treatment of infectious disease, cancer and B cell malignancy, are provided.

Materials and methods relating to fusion proteins an immune response

Growing community of inventors

Southampton, United Kingdom

Natalia Savelyeva