Pierre Fabre Dermo-cosmetique

Natacha Frison

Jean-Louis Brayer

Pascal Bordat

Jean-Hilaire Saurat

Sylvie Daunes-Marion

Roger Tarroux

Olivier Sorg

Benoit Folleas

Marie Charveron

Benoît Folleas

The invention concerns novel polyunsaturated compounds of formula (I) wherein: Rrepresents a R', -A-R&#x2032;group, R&#x2032;being selected from &#x2014;COOH, &#x2014;COOR, &#x2014;CONH, &#x2014;CONHR, &#x2014;CONRR, &#x2014;CHO, &#x2014;CHOH, &#x2014;CHOR, and A represents a C-Calkylene, alkenylene or alkynylene; Rrepresents: an optionally substituted aryl group or an optionally substituted heteroaryl group; a sugar residue or, a fatty acid residue optionally branched and/or substituted preferably at the chain terminus and particularly by hydroxy, acetoxy radical or by an optionally protected amino radical; a &#x2014;OC &#x2014;(CH)n CO-tocopheryl (alpha, beta or gamma or delta) group, with 2 $m(F) n $m(F) 10; a &#x2014;R&#x2032;&#x2014;O&#x2014;Rgroup, wherein R&#x2032;is an optionally substituted arylene group or an optionally substituted heteroarylene group, and Rrepresents a hydrogen atom, a straight or branched optionally substituted C-Calkyl, a straight or branched optionally substituted C-Calkenyl, or a straight or branched C-Calkynyl group, an optionally substituted tocopheryl radical or the like, an amino acid residue, or a sugar residue. The invention also concerns the compositions, in particular cosmetic and/or dermatological compositions containing at least one compound of formula (I) as well as their use as whitening and/or depigmenting agent, and the cosmetic method using said compositions.

Polyunsaturated compounds, method for preparing same and compositions containing the same

The invention concerns a method for preparing a compound of formula (I), wherein: Rand Rrepresent in particular H and n is greater than 4, said preparation method including performing a Wittig-Horner reaction with a phosphonate on a lactol, so as to obtain a hydroxyester and, optionally a saponification reaction of said hydroxyester.

Method for preparing unsaturated fatty hydroxyacids

Growing community of inventors

Creil, France

Natacha Frison