Horiba, Ltd.

Abx S.a.

Narihiro Oku

Yasuo Yamao

Hiroaki Uematsu

Junji Aoki

Takeshi Kohno

Kunio Terada

Seiji Usui

Hiroaki Takahasi

Yoshio Horii

Soichi Oue

Yoshihiro Yano

Takao Yoshii

Hitoshi Mitani

A nozzle device which can perform accurate quantitative suction without being affected by a pressure when, for example, a nozzle () is inserted into a closed container (T). The nozzle device has the nozzle () that is inserted into the closed container (T) and that sucks a liquid in the closed container (T), an exposure to atmosphere mechanism () that opens the closed container (T) to the atmospheric air, and an opening/closing structure () that is arranged at a proximal end of the nozzle () and that has an internal flow channel () communicated with a flow channel in the nozzle () and an opening/closing mechanism for opening and closing the internal flow channel (), and an opening/closing control section () that controls the opening/closing mechanism.

Nozzle device and liquid sample analyzer

The present invention provides an immunoassay method in which blood can be measured even without pretreatment by means of a centrifuge etc. In the present invention, antibodies or antigens in a sample are subjected to agglutination reaction with insoluble carriers onto which antigens or antibodies specifically reacting with the antibodies or antigens in the sample have been immobilized and the resulting agglutination mixture is determined for the change in its absorbance or in its scattered light by irradiation with light, wherein said sample is whole blood and the whole blood is forcibly lyzed.

Immunoassay method for lyzed whole blood

A compact combination blood cell count and immunoassay apparatus for measuring drawn whole blood specimen includes a load station for receiving the whole blood specimen and a nozzle member that can selectively withdraw whole blood from the blood specimen. A blood cell count section and an immunoassay section are mounted along a unitary path of movement of the nozzle member so that a single nozzle member may be used for transporting the whole blood to the respective blood cell count section and immunoassay section. A controller can automatically direct a transport mechanism to use only the whole blood and to perform various steps of adding dilution liquid and reagents, along with appropriate washing of the nozzle and sample cells to insure an automatic operation. A hematozorit value can be determined from the blood cell count signal and used to correct the immunoassay signal when whole blood is used.

Blood cell count/immunoassay apparatus using whole blood

An immunoassay method in which blood can be measured even without pretreatment by a centrifuge etc. In the present invention, antibodies or antigens in a sample are subjected to agglutination reaction with insoluble carriers onto which antigens or antibodies specifically reacting with the antibodies or antigens in the sample have been imrobilized and the resulting agglutination mixture is determined for the change in its absorbance or in its scattered light by irradiation with light, wherein said sample is whole blood and the whole blood is forcibly lysed.

Immunoassay method for lysed whole blood

A system collects fluid waste within a closed waste vessel where a waste disposal cycle is determined based upon the pressure level within the waste vessel. In the preferred embodiment, a closed liquid waste vessel accepts waste solutions through conduits having valves controlling conduit fluid communication with treatment vessels. A pressure sensor determines the level of pressure within the waste vessel. A pressurizing device reduces the level of pressure within the vessel. When the pressure within the vessel is lowered to a predetermined level, the valve is opened. When the pressure sensed within the liquid waste vessel then rises above an appointed value, the valve is closed, completing the waste collection of a treated sample. This corresponds to the point in time when the treatment vessel is empty, allowing a sudden rush of air into the waste vessel, raising the vessel pressure to ambient and closing the valve. When the pressure in the waste vessel does not rise to the appointed value after the lapse of a preset length of time, a warning signal is provided advising that the system is not working properly.

Apparatus for receiving liquid treatment samples for disposal

An improved pinch valve assembly for opening and closing flexible tubular conduits is provided. A housing member is capable of supporting flexible tubular conduits and contains an engagement member that is capable of closing the passageways through the flexible tubular conduit. The engagement member can configure to receive a stop member that is capable of restraining the engagement member at a position which prohibits closing of a flexible tubular conduits during non-operative storage and transporting modes of operation.

Pinch valve assembly with a storage mode

A standard solution for simultaneously calibrating a plurality of ion electrodes for determining a plurality of ion electrodes for determining a plurality of ions including at least potassium ions and calcium ions in blood, the improvement wherein the concentration of the standard solution for a potassium ion electrode and a calcium ion electrode is adjusted in accordance with the following equations: ##EQU1## As for potassium ion,

Standard solution for simultaneously calibrating a plurality of ion

A flow system glass electrode in use for pH measurement, which houses the glass electrode body in a resin block to improve an impact resistance, the glass electrode body being sealed by a packing to be small-sized and improve the degree of freedom in the direction of the use, sample flow tubes each being equal in an inner diameter to a response film and separate from the glass electrode body in order to eliminate stagnation of a sample liquid, enable the measurement of a minute sample, and facilitate manufacture and assembly of the electrode, the sample flow tubes being connected with a liquid inlet and a liquid outlet at the glass electrode body through couplings respectively.

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Miyanohigashi-machi, Japan

Narihiro Oku