Medtronic Vascular, Inc.

Medtronic Ave, Inc.

Kips Bay Medical, Inc.

Gentuity, LLC

Neograft Technologies, Inc.

C. R. Bard, Inc.

Edwards Lifesciences Corporation

480 Biomedical Inc.

Other

Medtronic, Inc.

Boston Scientific Scimed, Inc.

Mitralign, Inc.

Vascular Graft Colutions Ltd.

Nareak Douk

Nasser Rafiee

Morgan House

Peter Paul Zilla

Deon Bezuidenhout

Mark Yeoman

Thomas Franz

Michael F Wolf

Hellmut C Bowles

Peter Strickler

Paul Human

David S Brin

Rany Huynh

Eliot F Bloom

Christopher Petroff

Christopher L Petersen

William A Berthiaume

Jerry Brightbill

Richard A Gambale

R Maxwell Flaherty

Michael W Sutherland

Rany Busold

James F Crittenden

J Christopher Flaherty

Philipp Bonhoeffer

Richard J Morrill

Juan-Pablo Mas

Jonathan L Goodwin

David Barone

Kate E Cutuli

Michael Finney

Matt Guimond

Christopher Austin Battles

Lee A Core

Dennis L Brooks

Robert D Lashinski

Kicherl Ho

Albert Harold Dunfee

Michael Atlas

David W Kolstad

Giovanni J Ughi

My Le

Stuart Mac Donald

Matthew Rust

Timothy Robinson

Walter Bruszewski

John B Horrigan

William Asselin

Christopher Lee

Richard T Choh

Jonathan Morris

Douglas A Fogg

David R Erickson

Michael S Noone

Damian Jelich

Benedict Shia

Prema Ganesan

Curtis Hanson

Stuart R MacDonald

Bruce Adams

Jia Hua Xiao

James Machek

Sarah Kostanski

Troy Gardner

Christopher C Lee

Matthew S Poole

Steven Dapolito

James Stewart Hunter

Peggy Grills

Sonny Yamasaki

Barbara DeVaux

Steve Dapolito

David J Sauvageau

Ahmed Malek

Michael C Wolf

Chirstopher Lee

Jiyuan Yin

Lindsy Peterson

Helmut Bowles

Matt S Poole

Ellen M Jennings

Timothy P Collins

Heng Mao

Rany Huynh Busold

Stuart R Macdonald

Jonathan Goodwin

An imaging system for a patient comprises an imaging probe. The imaging probe comprises: an elongate shaft for insertion into the patient and comprising a proximal end, a distal portion, and a lumen extending between the proximal end and the distal portion; a rotatable optical core comprising a proximal end and a distal end, and at least a portion of the rotatable optical core is positioned within the lumen of the elongate shaft; an optical assembly positioned proximate the distal end of the rotatable optical core, the optical assembly configured to direct light to tissue and collect reflected light from the tissue; a damping fluid positioned between the elongate shaft and the rotatable optical core and configured to reduce non-uniform rotation of the optical assembly; and a fluid pressurization element configured to increase the pressure of the damping fluid to reduce the presence of bubbles proximate the optical assembly.

Imaging probe with fluid pressurization element

An imaging system for a patient is provided. The system includes an imaging probe having an elongate shaft with a proximal end, a distal portion, and a lumen extending between the proximal end and the distal portion. A rotatable optical core is positioned within the lumen of the elongate shaft. An optical assembly is positioned proximate the distal end of the rotatable optical core and is configured to direct light to tissue and collect reflected light from the tissue. An imaging assembly is constructed and arranged to optically couple to the imaging probe and the imaging assembly is configured to emit light into the imaging probe and receive the reflected light collected by the optical assembly.

Imaging system with optical pathway

A catheter system including a wire, a translatable catheter, and first and second tethers is introduced into a body of a subject. The translatable catheter has a curved portion proximate a distal end of the translatable catheter. The first tether is coupled to the wire, and passes proximally through the translatable catheter. The second tether is attached to the curved portion. The catheter system is positioned such that the wire is disposed at a first location in the body. While the wire remains at the first location, the translatable catheter is translated away from the wire by manipulating the first tether and the second tether. Other embodiments are also described.

Translation catheters, systems, and methods of use thereof

An imaging system for use in a patient is provided. The system includes an imaging probe, a rotation assembly, and a retraction assembly. The imaging probe collects image data from a patient site and includes an elongate shaft with a proximal end and a distal portion, with a lumen extending therebetween. A rotatable optical core is positioned within the elongate shaft lumen and an optical assembly is positioned in the elongate shaft distal portion. The optical assembly directs light to tissue at the patient site and collects reflected light from the tissue. The rotation assembly connects to the imaging probe and rotates the optical assembly. The retraction assembly connects to the imaging probe and retracts the optical assembly and the elongate shaft in unison.

Imaging system

An imaging system for a patient comprises an imaging probe. The imaging probe comprises: an elongate shaft for insertion into the patient and comprising a proximal end, a distal portion, and a lumen extending between the proximal end and the distal portion; a rotatable optical core comprising a proximal end and a distal end, the rotatable optical core configured to optically and mechanically connect with an interface unit; a probe connector positioned on the elongate shaft proximal end and surrounding at least a portion of the rotatable optical core and an optical assembly positioned in the elongate shaft distal portion and proximate the rotatable optical core distal end, the optical assembly configured to direct light to tissue and collect reflected light from the tissue. A shear-thinning fluid can be provided between the elongate shaft and the rotatable optical core, such as to reduce undesired rotational variations of the rotatable optical core.

Micro-optic probes for neurology

The present teachings generally relate to translation catheter systems and method of using thereof in treating defective mitral valves. Specifically, a translation catheter system includes a catheter configured to move substantially laterally along the mitral annulus and the lateral movement of the catheter is substantially continuous and substantially adjustable. Accordingly, a method of using such a translation catheter includes advancing a first wire across the mitral annulus at a first treatment location, delivering a catheter at or near the first treatment location, moving the catheter substantially laterally to a second treatment location, and advancing a second wire across the mitral annulus, where the distance between the first and second treatment locations is substantially adjustable and optionally visualized.

Stents and methods of using stents are provided. Stents of the invention provide external support structure for a blood vessel segment disposed within, wherein the stents are capable of resilient radial expansion in a manner mimicking the compliance properties of an artery. The stent may be formed of a knitted or braided mesh formed so as to provide the needed compliance properties. A venous graft with the stent and a vein segment disposed within is provided, wherein graft is capable of mimicking the compliance properties of an artery. Methods of selecting stents for downsizing and methods of using the stents of the invention in downsizing and smoothening are provided. Methods of replacing a section of an artery with a venous graft including a stent of the invention are provided. Methods of reducing intimal hyperplasia in implanted vein segment in a venous graft using stents of the invention are provided.

Graft apparatus

Described is a delivery system for minimally invasive delivery of a self-expandable stent to a body lumen, and particularly delivery of a prosthetic valve to the right ventricular outflow tract. Also described is a method of loading a stent onto such a delivery system, and a method of delivering a self-expandable stent to a desired anatomic site.

Infundibular reducer device delivery system and related methods

Translation catheters and systems

A graft includes a flexible, resilient, generally tubular external support and a blood vessel segment, carried within and having an ablumenal surface in contact with and supported by the tubular support, the graft being capable of resilient radial expansion in a manner mimicking the radial compliance properties of an artery.

Compliant blood vessel graft

Delivery systems for a polymeric tubular implant, kits that include such delivery systems, and methods of treating patients by implanting tubular implants using the delivery systems. The delivery systems include an inner shaft, an expandable member slidably disposed about the inner shaft and configured to receive the tubular implant, and a tubular outer shaft disposed about the inner shaft.

Polymeric implant delivery system

A device and related methods of use are provided for the capture and removal of various unwanted objects present within the body's anatomical lumens. In an embodiment of the present disclosure, the device includes a sheath, a cutting device, an elongate member, and a retrieval assembly connected to the elongate member and retractable within and extendable from a lumen extending through the sheath and cutting device.

Cutting device and related methods of use

Growing community of inventors

Lowell, MA, United States of America

Nareak Douk