Ube Industries, Inc.

Daiichi Sankyo Company, Limited

Naoyuki Yokota

Kikuo Ataka

Yasuhito Yamamoto

Hiroshi Yoshida

Yasuhiro Yoneda

Kensaku Fuse

Yoshitaka Onduka

Masahiko Hagihara

Teruhiko Inoue

Hiroyuki Miyata

Kazuhiro Morita

Kiyoshi Ohmori

Yukinori Wada

Masahiko Kohno

Kazuyoshi Nakamura

The present invention is directed to providing prasugrel hydrochloride or the like with a reduced content of OXTP. A method for producing prasugrel hydrochloride with a reduced content of OXTP, comprising dissolving free prasugrel containing OXTP in an inert solvent and adding hydrochloric acid optionally dropwise to the solution for reaction is also provided.

Process for producing high-purity prasugrel and acid addition salt thereof

4-fluoro-3-oxocarboxylic esters and process for producing the same

6-(1-fluoroalkyl)-4-pyrimidones and processes for producing the same

The present invention is to provided a trifluoro-substituted benzoic acid, an ester thereof, particularly 2,3,4-trifluoro-5-iodobenzonic acid, 2,3,4-trifluoro-5-trifluoromethylbenzonic acid, esters thereof, which are useful as a starting material for synthesizeing a quinolonecarboxylic acid compound useful as a medicine, an anti-bacterial agent or an antiviral agent, and processes for preparing these compounds and 2,4,5-trifluoro-3-iodobenzonic acid, 2,4,5-trifluoro-3-trifluoromethylbenzoic acid and esters thereof.

Trifluoro-substituted benzoic acid, esters thereof and processes for preparing the same

Trifluoro-substituted benzoic acid, esters thereof, and process for

2-silyloxy-tetrahydrothienopyridine, salt thereof and process for

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Ube, Japan

Naoyuki Yokota