Kao Corporation

Naonobu Yoshizuka

Genji Imokawa

Toshiaki Osawa

Tadashi Hase

Shuichi Akazaki

Michihiro Hattori

Eijiro Takeuchi

Eisaku Yoshida

Masaaki Yoshimura

The present invention relates to a monoclonal antibody which specifically binds to a peptide having amino acid sequence (I) described below or having in part at least continuous 4 amino acid sequences of the amino acid sequence (I), and also to a process for producing a monoclonal antibody capable of specifically binding to the peptide represented by the following amino acid sequence:

Monoclonal antibody specific for a human macrophage chemotactic factor

The present invention relates to physiologically active peptides and more particularly, to novel peptides having a specific amino acid sequence which possess a macrophage chemotactic activity.

Novel peptides possessing a macrophage chemotactic activity

Novel cosmetic compositions comprising a lipid derived from horny cells can enhance a moisture retention ability of the horny layer and are useful for remedy of dry skin. When the lipid is used in combination with surface active agents, the above effect is enhanced. The cosmetic compositions may take any preparations such as creams, milky lotions, beauty wash, rouges, foundations, hair tonics and the like.

Cosmetic compositions

Sebum secretion accelerator composition comprising a cholesteryl ester of a branched fatty acid represented by the formula (I): ##STR1## in which R represents a saturated aliphatic hydrocarbon group having from 11 to 23 carbon atoms and at least one alkyl substituent at a position between the carboxyl bond and the center of the main chain. The cholesteryl ester should be contained not smaller than 25 wt % of the total composition. The composition according to the invention promotes sebum secretion, and is effective in keeping healthy and beautiful skin. The composition is further advantageous in that it can be readily formed into various types of cosmetics such as lotions, creams and ointments.

Growing community of inventors

Tochigi, Japan

Naonobu Yoshizuka