Osaka Bioscience Institute

Maruha Corporation

Other

Riken Corporation

Japan Science and Technology Corporation

Taiho Pharmaceutical Company Limited

Kurashiki Boseki Kabushiki Kaisha

Naomi Eguchi

Yoshihiro Urade

Hiroshi Oda

Nobuyuki Sato

Kosuke Seiki

Kosuke Aritake

Hiroshi Takenaka

Masazumi Nishikawa

Hiroshi Nakajima

Hideaki Hikawa

Masashi Miyano

Satoru Takeda

Yasuhisa Sakurai

Shuuichi Taneda

Yasuhiko Shiina

Mitsuhito Mase

Hiroya Nakau

Takashi Inui

Ryo Kawata

Yo Sato

Masako Taniike

Ikuko Mori

Yutaka Eguchi

Sawako Hyo

Sawako 128 Takatsuji-Omiya-Cho Hyo

Yoshihiro 503 Granshitio-Shimogamo-Shikisaikan Urade

A method is provided for diagnosis of the severity of a condition in an eosinophilic inflammatory disease such as nasal polyp and for prediction of the recurrence of the disease.

Method for diagnosis of severity and prediction of recurrence in eosinophilic inflammatory disease

In a method for automatically detecting degenerated regions in many stained thin section specimens (), color region information is obtained on a degenerated region and on a non-degenerated region on image data of a standard specimen in a stained thin section slide. Next, color region information is obtained on a non-degenerated region on image data of a specimen. Next, the image data of the specimen is compared with the image data of the standard specimen to calculate a color correction quantity to match tone and brightness of the non-degenerated region in the specimen with the counterparts in the non-degenerated region in the standard specimen, and the image data of the specimen is corrected with the color correction quantity. Next, a degenerated region is extracted in the corrected image data of the specimen based on the color region information in the standard specimen.

Method for automatically detecting degenerated regions in stained thin section slides

Provided are: a method for predicting the onset of pregnancy-induced hypertension (PIH) by precisely detecting abnormalities that occur before the onset of PIH (where such abnormalities have been impossible to detect by various conventional testing methods for PIH) while imposing less of a burden on a subject; a method for evaluating a fetus and placental functions in PIH; and a method for detecting PIH, which comprises measuring the level of human lipocalin-type prostaglandin D synthase (L-PGDS) in a body fluid sample collected from a subject.

Method for predicting pregnancy-induced hypertension

The present invention relates to methods for differentiating demential diseases comprising measuring the concentration of human lipocalin-type prostaglandin D synthase in a sample of a body fluid collected from a subject and kits for differentiating demential diseases comprising an antibody specific to human lipocalin-type prostaglandin D synthase.

Methods to facilitate diagnosis of normal pressure hydrocephalus

An object of the present invention is to provide a method which is able to prevent or improve the progress of myolytic diseases such as muscular dystrophy. Such an object is able to be solved by a method where an effective dose of an inhibitor for hematopoietic prostaglandin D synthase (H-PGDS) or an antagonist to prostaglandin D receptor is administered to a patient who needs it. The present invention also provides a method for screening compounds which are able to prevent the progress of myolytic diseases and to improve it using human H-PGDS overexpressed transgenic mice.

Method for treating myolytic disease and method for screening antimyolytic agent

The present invention provides a method for detecting or predicting ischemic disorders in a subject by using as an indication the concentration of human lipocalin-type prostaglandin D synthase (hPGDS) in body fluid samples from the subject. More specifically, the method comprises comparing the hPGDS concentrations in the body fluid samples from a subject with the reference values established for a normal subject, thereby detecting or predicting the ischemic disorders.

Methods and kits for detecting or predicting ischemic disorders

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Suita, Japan

Naomi Eguchi