Asahi Medical Co., Ltd.

Asahi Kasei Kogyo K.k.

Naokuni Yamawaki

Tatsuya Fukuda

Takao Nishimura

Hiroyuki Watanabe

Tadashi Yokoyama

Disclosed is a filter material for selectively removing leukocytes from a leukocyte-containing suspension, which comprises a porous element having an average pore diameter of 1 to 25 .mu.m and a total pore volume of 0.40 to 0.95 ml/ml of the porous element, and wherein the sum of respective pore volumes of pores of the porous element which have a pore diameter of 1 to 30 .mu.m is 90% or more, based on said total pore volume. Also disclosed is a filter apparatus for selectively removing leukocyte from a leukocyte-containing suspension which is packed with the above-mentioned filter material. By virtue of the filter material, the filter apparatus not only can remove leukocytes from a leukocyte-containing suspension at a leukocyte removal efficiency as excellent as 10.sup.-4 or less in terms of a leukocyte residual ratio without suffering from a pressure loss increase, but also can be rendered compact.

Filter apparatus for selectively removing leukocytes

Filter material for selectively removing leukocytes

An adsorbent for .beta..sub.2 -microglobulin is disclosed, which comprises a water-insoluble carrier having supported thereon, as a ligand, at least one electrolyte selected from the group consisting of a polyamino acid, a polysaccharide, a synthetic high polymer, collagen having an isoelectric point of 9.5 or more, and gelatin having an isoelectric point of 6.5 or more, wherein said electrolyte has a molecular weight not less than 1,000 and an X value of more than 2.0, wherein X is a relationship regarding the skeleton structure of said electrolyte and is the sum of A and B, wherein A represents (the number of carbon atoms of the skeleton structure)-(the number of hydrophilic groups)/(the number of hydrophilic groups); and B represents .vertline.(the number of cationic groups)-(the number of anionic groups).vertline./(the number of hydrophilic groups). The adsorbent exhibits adsorptivity for .beta..sub.2 -microglobulin at high efficiency and high selectivity.

Absorbent of .beta..sub.2 -microglobulin

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Oita, Japan

Naokuni Yamawaki