Ajinomoto Co., Ltd.

Naoko Kanno

Kunisuke Izawa

Takayuki Suzuki

Masakazu Nakazawa

Satoshi Katayama

Yutaka Honda

Toru Ikeda

Susumu Shibahara

Nobuyoshi Kitamura

Hiromi Suzuki

Compounds formed by reacting a protected amino acid with an alkali metal enolate of an alkyl acetate are reacted with a halogenating agent for halogenation of the 2-position, or a protected amino acid is reacted with an alkali metal enolate of an alkyl halogenoacetate, to form a 4-amino-3-oxo-2-halogenobutanoic acid ester derivative, and hydrolysis and decarboxylation are conducted to produce a 3-amino-2-oxo-1-halogenopropane derivative or its salt. The present method is a useful process for producing a 3-amino-2-oxo-1-halogenopropane derivatives which can easily be converted to a 3-amino-1,2-epoxypropane.

Process for producing 3-amino-2-oxo-1-halogenopropane derivatives

The invention relates to biologically active substances coated with a coating composition containing at least one substance selected from the group consisting of hardened vegetable fats and oils, hardened animal fats and oils, fatty acid esters and phospholipids and an enzyme and/or enzyme activator where the outermost surface portion of the coating layer contains substantially no enzyme and/or enzyme activator. The invention materials exhibit excellent protection in the rumen of ruminant animals and allow for the dissolution in the post-abomasum lower digestive organs of the ruminant.

Granular feed additives for ruminants containing lipase, bile powder and

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Kawasaki, Japan

Naoko Kanno