Sanwa Kagaku Kenkyusho Co., Ltd.

Naoki Takahashi

Hiroki Nagano

Mitsuaki Takeuchi

Toshiyuki Miyazawa

Morio Okabe

Toru Izuchi

Satoko Harada

Daisuke Kurumazuka

Yuka Kuno

Katsunori Kitamoto

Nobuyoshi Kasugai

Hiroyo Kataoka

Yasushi Ohsawa

Hiroki Fujieda

Keita Sakai

Izumi Gotoh

Yukiyasu Asano

Yurie Yamada

A compound having a V2 receptor agonistic activity is provided. Providing a pharmaceutical composition which contains, as an active ingredient, a compound represented by general formula (I) described below: [Ris formula described below: (A is a lower alkylene group which may be substituted with lower alkyl group; Ris a hydrogen atom; Ris a hydroxyl group, an aromatic heterocyclic group which may be substituted with lower alkyl group, carbamoyl group); Ris a hydrogen atom or lower alkyl group; Ris lower alkyl group which may be substituted with 1-3 fluorine atoms, or halogen atom; Ris a five-membered aromatic monocyclic heterocyclic group, five-membered non-aromatic monocyclic heterocyclic group, (provided each heterocyclic groups contain at least one nitrogen atom and may be substituted with a lower alkyl group); and Ris a lower alkyl group, halogen atom], or pharmacologically acceptable salt thereof.

Benzoazepine derivative and medical use thereof

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Kuwana, Japan

Naoki Takahashi