Japan Tobacco Inc.

Naoki Ogawa

Taku Ikenogami

Takashi Nakagawa

Teruhiko Inoue

Masanori Shindo

Yuko Shinagawa

Toshihiro Kiguchi

Yuki Soejima

Takuya Matsuo

Takahiro Oka

Takayuki Yamasaki

Kazutaka Ikegashira

Tatsuya Matsumoto

Kenji Fukuda

Compounds of formula [I]: wherein each symbol is as defined in the description,or a pharmaceutically acceptable salts or solvates thereof.

Azetidine compound and pharmaceutical use thereof

A compound represented by the following formula (1), a pharmaceutically acceptable salt thereof or an optically active form thereof: wherein each symbol is as defined in the specification. A compound having a calcium-sensing receptor antagonistic action, a pharmaceutical composition comprising the compound, particularly a calcium receptor antagonist and a therapeutic drug for osteoporosis are provided.

CaSR antagonist

The present invention provides a compound having a calcium-sensitive receptor antagonistic action, a pharmaceutical composition containing the compound, particularly a calcium receptor antagonist and a therapeutic drug for osteoporosis. A compound represented by the following formula (1), a pharmaceutically acceptable salt thereof or an optically active form thereof: wherein each symbol is as defined in the description.

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Takatsuki, Japan

Naoki Ogawa