Sumitomo Chemical Company, Limited

Other

Chugai Seiyaku Kabushiki Kaisha

Kowa Company Limited

International Business Machines Corporation

National Institute for Agro-environmental Sciences Independent Administrative Institute

Sakai Toshiyuki

National Institute for Agro-environmental Sciences Independent Administration Institute

Naoki Harada

Takashi Omura

Yutaka Kayane

Kingo Akahori

Tetsuya Miyamoto

Hirokazu Sawamoto

Kazufumi Yokogawa

Toshihiko Morimitsu

Akira Takeshita

Sadanobu Kikkawa

Shigeru Kawabata

Yasuo Tezuka

Takeshi Washimi

Shuhei Hashizume

Kazuhiro Takagi

Miyao Takahashi

Masahiro Sakaitani

Hitoshi Iikura

Masayuki Matsushita

Fumio Watanabe

Sawako Ozawa

Toshihiro Aoki

Noriyuki Furuichi

Takahiko Fujisaki

Pil-Su Ho

Yasushi Tomii

Kenji Takanashi

Ikumi Hyoudoh

Kazuya Ogino

Masayuki Miki

Yuuichi Yoshioka

Mikoto Takahashi

Susumu Shimotono

Akio Iwasaki

Toshio Nakamatsu

Kunihiko Imada

Sadaharu Abeta

Yosuke Yamamoto

Takehiro Kusumoto

Hideo Kawashita

Toshiyuki Sakai

Noriaki Yamauchi

Takemi Tokieda

Katsumasa Otake

Yoshiteru Ohta

Shinei Ikeou

Mahito Fujita

Masahiko Shinomura

Hiroyuki Suzuki

Junya Hada

Mituhiro Ohta

Isao Nakamae

Nobuaki Kawamura

Yasutaka Shimidzu

Minoru Morikawa

Kazumi Yoshigoe

Haruo Sugi

Mayumi Takahashi

Ken Inoue

Kunihiko Fujii

Syuhei Hashizume

Miwako Fujii

Koiti Ishii

Yasuji Mori

Takahiko Fuzisaki

Hideyuki Tagai

The present invention provides a p27 protein inducing agent comprising a compound represented by general formula (11) below or pharmaceutically acceptable salt thereof as an active ingredient: wherein G, G, Gand Gare each independently selected from &#x2014;N&#x2550; etc., Ring Gis selected from divalent aryl etc., A is selected from amino etc., Gis selected from oxygen etc., Gis selected from oxygen etc., Gis selected from &#x2014;CH&#x2014; etc., and Ris selected from Calkyl etc.

p27 protein inducer

The present invention provides a stable complex microbial system, which simultaneously decomposes a plurality of organic contaminants even under a polluted environment with these contaminants and permits more effective decomposition of persistent organic contaminants such as PCNB and simazine. A support for holding a complexed accumulation of degrading bacteria, which contains a porous material provided as a support on which a degrading bacterium A capable of degrading at least one organic contaminant and a degrading bacterium B capable of degrading another organic contaminant are accumulated, is produced. The degrading bacterium A may be a PCNB-degrading bacterium, particularly a degrading bacterium containing a degrading bacterium having part or all of mycological characteristics ofsp. PD653 and the degrading bacterium B may be a degrading bacterium containing a degrading bacterium having part or all of mycological characteristics of &#x3b2;-CDB21.

Method of decontaminating polluted environments with bacteria on a porous support

The present invention provides a compound represented by general formula (1) below or a pharmaceutically acceptable salt thereof: wherein: X is selected from heteroaryl etc., Yand Yare selected from &#x2014;N&#x2550; etc., Yand Yare selected from &#x2014;CH&#x2550; etc., A is selected from sulfamide etc., Ris selected from hydrogen etc., and Ris selected from Calkyl etc. The compound or salt has sufficiently high antitumor activity, and is useful in the treatment of cell proliferative disorders, particularly cancers. The present invention also provides a pharmaceutical composition containing the compound or salt as an active ingredient.

Coumarin derivative having antitumor activity

Disclosed are: a novel microorganism which can decompose a methylthiotriazine compound (particularly, simetryn, dimethametryn, prometryn), a chlorotriazine compound (particularly, simazine, atrazine, propazine) and a methoxytriazine compound (particularly, simeton, atraton, prometon) which have been frequently used as agrichemicals or the like; and a method for decomposing a methylthiotriazine compound, a chlorotriazine compound and/or a methoxytriazine compound by using the microorganism. Specifically disclosed are: a novel bacteriumsp. strain MTD22 which is capable of decomposing a methylthiotriazine compound, a chlorotriazine compound and a methoxytriazine compound; and a method for decomposing a methylthiotriazine compound, a chlorotriazine compound and/or a methoxytriazine compound, particularly simetryn, dimethametryn, prometryn, simazine, atrazine, propazine, simeton, atraton and/or prometon, by using the microorganism.

Microorganism capable of microbially decomposing chloro-, methylthio- and methoxy-triazine agrichemicals

Disclosed are: a microorganism capable of degrading diphenylarsinic acid; a method for degrading diphenylarsinic acid by using the microorganism; a method for clean-up of a contaminated soil by using the microorganism; an agent for degrading diphenylarsinic acid, which comprises the microorganism; and a cleaning agent for a contaminated soil or groundwater, which comprises the microorganism. Specifically disclosed are: a microorganism belonging to the genusand capable of degrading diphenylarsinic acid; a microorganism belonging to the genusand capable of degrading diphenylarsinic acid; a method for clean-up of a contaminated soil by using the microorganism; an agent for degrading diphenylarsinic acid, which comprises the microorganism; and a cleaning agent for a contaminated soil or groundwater, which comprises the microorganism.

Microorganism capable of degrading diphenylarsinic acid

The present invention provides a stable complex microbial system, which simultaneously decomposes a plurality of organic contaminants even under a polluted environment with these contaminants and permits more effective decomposition of persistent organic contaminants such as PCNB and simazine. A support for holding a complexed enrichment of degrading bacteria, which contains a porous material provided as a support on which degrading bacteria A capable of degrading at least one organic contaminant and degrading bacteria B capable of degrading another organic contaminant are enriched, is produced. The degrading bacteria A may be a PCNB-degrading bacteria, particularly degrading bacteria containing degrading bacteria having part or all of the bacteriological characteristics ofsp. PD653 and the degrading bacteria B may be degrading bacteria containing degrading bacteria having part or all of the bacteriological characteristics of &#x3b2;-Proteobacteria CDB21.

[object Object]

A gene encoding an IgG Fc region-binding protein (FC&ggr;BP); a recombinant vector containing this gene; host cells transformed by this recombinant vector; a process for producing a recombinant protein which is obtained by incubating these host cells; and a protein having a recombinant IgG Fc region-binding activity which is obtained by the above-mentioned process.

Gene encoding IGG FC region-binding protein

An asymmetric dioxazine compound represented by the following formula (I) in the free acid form: ##STR1## wherein A.sub.1 and A.sub.2 independently of one another are each sulfo, halo, alkyl or alkoxy, X.sub.1 and X.sub.2 independently of one another are each hydrogen, halo, alkyl, alkoxy or phenoxy, R.sub.1 is hydrogen or unsubstituted or substituted alkyl, R.sub.2 and R.sub.3 independently of one another are each hydrogen, alkyl, alkoxy, halo or unsubstituted or substituted amino, Z is a fiber-reactive group, m and n independently of one another are each 0 or 1, provided that m.noteq.n, and L is 1 or 2. This compound is suitable for dyeing and printing cellulose fiber, natural and synthetic polyamide fibers, polyurethane fiber, leather and the like and mixed yarns thereof, to obtain dyed or printed products of a color fast to light, wetness and chlorine with superior build-up and level dyeing properties.

Asymmetric dioxazine compounds and method for dyeing or printing fiber

Disclosed is a data processing apparatus that has two or more internal SCSI devices, to include a SCSI controller, that can also accommodate eternal SCSI devices via a port connector and that can manage the ID numbers (identification numbers) of the internal SCSI devices separately from all the other SCSI devices without requiring any action by a user; and a method for controlling such a data processing apparatus. According to the present invention, ID numbers can be written into internal SCSI devices. ID numbers that do not collide with the ID numbers of the externally connected SCSI devices are assigned to the respective internal SCSI devices. The system can automatically write the ID numbers during the booting process or when the system configuration is physically changed. Even when there are SCSI hard disk drives installed both inside and outside the system, the ID numbers of the SCSI hard disk drives that are internally positioned can be read so that the internal SCSI hard disk drives can be designated. When a system enters into a hibernation mode because the remaining capacity of a battery falls low, an internal SCSI hard disk can be designated as a hibernation target to which a hibernation file is saved.

Small computer system interface ('SCSI') controller

An asymmetric dioxazine compound of the following formula: ##STR1## wherein R is sulfo, halogeno, alkoxy, alkyl or carboxy; R.sub.1 and R.sub.2 are each hydrogen or alkyl; R.sub.3 is hydrogen, alkyl or acyl; X.sub.1 and X.sub.2 are each hydrogen, halogeno, alkyl, alkoxy or phenoxy; Y is aliphatic amino having a vinylsulfonyl or .beta.-substituted ethylsulfonyl fiber-reactive group; and Q is unsubstitued, substituted or cyclic amino; is useful for dyeing or printing fiber materials blue with excellence in build-up properties and various fastness properties.

Asymmetric dioxazine compounds and use thereof as fiber reactive dyes

A computer unit and multiple I/O adapter units are interconnectable in a variety of different plug attachment configurations which may be frequently altered in normal use of the system. An arrangement is provided for automatically initializing adapter units which are currently connected to the computer unit to operating states uniquely suited to the current configuration of connections. In the arrangement, non-volatile storage means retentively stores multiple sets of configuration state information, each set corresponding to a different configuration of connections between the adapter units and the computer unit. Means operating during each initialization of the system detects identities (ID's) of adapter units currently connected to the computer unit, and compares them to ID's associatively stored with the configuration state information. When a corresponding set of ID's is found, the associated configuration state information is retrieved and used for initializing the currently connected adapter units to operating states uniquely suited to the detected configuration of ID's. In the disclosed embodiment, information associated with the adapter unit configuration existing when system power was last turned off is stored in both a non-volatile RAM (NVRAM) and in a reserved area of a hard disk drive (HDD) which holds information associated with both the presently existing adapter configuration and previously existing configurations. Detected ID's of currently connected adapter units are compared first to identity information in NVRAM, and if a match is detected the associated state information in NVRAM is used to initialize the currently connected adapter units. If a mismatch is detected, the detected unit ID's are compared to sets of ID's contained in index functions stored in the HDD. If a match is found in this comparison, configuration state information associated with the respective index function is retrieved, written to NVRAM and applied to the currently connected adapter units. This arrangement is particularly useful for automatically initializing portable computer systems which can operate either standalone or docked/connected to one or more desktop expansion units.

Automatic reconfiguration of alterable systems

Herein is provided a trisazo compound represented by formula (I) in the free acid form: ##STR1## wherein Q.sub.1 is an unsubstituted or substituted phenylene or naphthylene group, Q.sub.2 is an unsubstituted or substituted phenyl or naphthyl group, Z is --SO.sub.2 CH.sub.2 CH.sub.2 OH or --SO.sub.2 CH.sub.2 CH.sub.2 SO.sub.3 H group, and L is 0 or 1. The trisazo compound provided herein is excellent in solubility and gives deep colored dyed product or image when used in dyeing or printing, so that it is useful as a dye and an ink. Herein are also provided a method for dyeing fiber materials, paper or leather by using said trisazo compound, and an ink containing said trisazo compound.

Trisazo compounds, method for dyeing fiber materials, paper or leather

A dioxazine compound represented by the following formula in the free acid form, ##STR1## wherein V is a direct linkage or ##STR2## in which R.sub.3 is hydrogen or alkyl, X is a direct linkage or an aliphatic, araliphatic or aromatic bridging group, Y is phenylene or naphthylene, Z is a so-called vinylsulfone type fiber reactive group, and R.sub.1 and R.sub.2 are each hydrogen or alkyl, which is useful for dyeing or printing fiber materials to give a dyed or printed product of a blue color superior in fastness properties with superior build-up property.

Dioxazine blue dye compound having vinylsulfone type fiber reactive

An asymmetric dioxazine compound represented by the following formula (I) in the free acid form: ##STR1## wherein A.sub.1 and A.sub.2 independently of one another are each sulfo, halo, alkyl or alkoxy, W is an unsubstituted or substituted aliphatic or aromatic bridging group, X.sub.1 and X.sub.2 independently of one another are each hydrogen, halo, alkyl, alkoxy or phenoxy, R.sub.1 and R.sub.2 independently of one another are each hydrogen or unsubstituted or substituted alkyl, R.sub.3 and R.sub.4 independently of one another are each hydrogen, halo, alkyl, alkoxy or unsubstituted or substituted amino, Z is a fiber-reactive group, m and n independently of one another are each 0 or 1, provided that m.noteq.n, and l is 1 or 2. This compound is suitable for dyeing and printing cellulose fiber, natural and synthetic polyamide fibers, polyrethane fiber, leather and the like and mixed yarns thereof, to obtain dyed or printed products of a color fast to light, wetness and chlorine with superior build-up and level dyeing properties.

Growing community of inventors

Ibaraki, Japan

Naoki Harada