Other

Neogenestar LLC

Nancy Quan

Thor W Nilsen

Zheng Wang

This disclosure describes a novel, ready-to-use protease composition in the form of a film or pouch composition. The protease composition can be used for stabilizing a biological sample containing a nucleic acid molecule for storage or transportation. It allows quick removal of protein contamination in the biological sample, thus facilitating sample preparation for nucleic acid detection or extraction.

Protease compositions and methods of use thereof

A device for capturing and releasing magnetically susceptible particles includes a housing and a retraction mechanism. A permanent axially magnetized cylindrical magnet is coupled to the retraction mechanism and a distal end of the magnet extends from a distal end of the housing. The retraction mechanism is configured to position the distal end of the magnet at one of three different predetermined distances from the distal end of the housing: retracted, protracted and hyper-protracted. A sleeve is provided over the housing distal end and when the magnet is in the protracted position, magnetically susceptible particles are gathered, when in the retracted position, magnetically susceptible particles are released and the sleeve is ejected when the magnet is positioned at a point between the protracted and the hyper-protracted position.

Device for capturing and releasing magnetic particles

Disclosed is a process for isolating cell-free nucleic acid (including both DNA and RNA) or an analog thereof from a bodily fluid, and which entails: a) mixing in a container the bodily fluid, a chaotropic agent in solid form, a detergent and a buffer, and a solid phase which includes magnetic particles, thus forming a reaction mixture containing the cell-free nucleic acid; b) magnetically separating the solid phase having the cell-free nucleic acid bound thereto from the reaction mixture; and optionally c) dissociating the nucleic acid from the solid phase. Compositions and kits are also disclosed.

Growing community of inventors

Warren, NJ, United States of America

Nancy Quan