National Institute of Advanced Industrial Science and Technology

Oriental Yeast Co., Ltd.

Nisshin Seifun Group Inc.

Sapporo Holdings Limited

Nanako Itoh

Koyomi Miyazaki

Kenji Kasuya

Keiko Tanaka

Yasukazu Nakakita

Yosuke Kikuchi

Yoshiaki Onishi

Saori Yamamoto

Tatsunosuke Tomita

Katsutaka Ooishi

Shinichi Fukudome

Hirotaka Kaneda

Katsutaka Oishi

The invention provides an agent for improving circadian rhythm comprising cells of lactic acid bacterium or treated product thereof as an active ingredient.

Circadian rhythm-improving agent

Disclosed are a method of preparation and method of application of a circadian rhythm regulatory agent having as an active ingredient an alkylresorcinol represented by general formula (I) below and a circadian rhythm regulatory agent containing as an active ingredient an alkylresorcinol-containing extract from a cereal or a nut containing an alkylresorcinol of the following general formula (I). In the following general formula (I), Ris a saturated or unsaturated alkyl group; and Ris hydrogen or methyl. In general formula (I), Ris preferably at the para-position with respect to R, and Ris preferably a saturated or unsaturated alkyl group having 15 to 27 carbon atoms. [Chem. 1] 

Method of regulating circadian rhythm, and method of preparing circadian rhythm regulatory agent

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Tsukuba, Japan

Nanako Itoh