Korea Institute of Science and Technology

Other

Chungbuk National University Industry-Academic Cooperation Foundation

Nakwon Choi

Eui Sung Yoon

Soo Hyun Lee

ChangJoon Justin Lee

Il-Joo Cho

Sohyun Kim

Dong Jin Lee

Hyung Min Kim

Byung Chul Lee

Hye Jin Kim

Sang Kyung Kim

Ji Yoon Kang

Seon Joon Kim

Mina Kim

Ki Joo Pahk

Seungwon Jung

Kyoseon Hwang

Jinsik Kim

Yong Kyoung Yoo

Hong-Nam Kim

Mintack Oh

Hyogeun Shin

Hong Nam Kim

Byung Chui Lee

Hyejeong Seong

Hyungbeen Lee

Hong-Jun Lee

Eun Yeong Yang

Eun-Mi Hur

Sohyeon Jeong

Sun-Kyoung Im

Sang-Hoon Cha

Hyunsu Lee

Sang Yun Yeom

Woongsun Choi

The disclosure relates to a MXene-polymer composite comprising MXene and a UV curable polymer, and a sensor comprising the same. Particularly, the MXene-polymer composite according to the disclosure polymerizes the MXene with the UV-curable polymer to stably disperse the MXene in a porous hydrogel matrix, thereby exhibiting a larger surface area and enabling local patterning, and when the MXene-polymer composite is applied as a sensor, excellent electrochemical sensitivity and gas reactivity can be obtained.

MXene-polymer composite comprising MXene and UV curable polymer, and sensor comprising the same

A high resolution fluorescence imaging device includes a light guide plate having a fluid channel which allows a solution containing a fluorescent sample to pass; a light source disposed on a side of the light guide plate to irradiate light inward the light guide plate; an image sensor disposed under the light guide plate; and a thin film interposed between the light guide plate and the image sensor, wherein the thin film has a first surface having a plurality of pillars and a second surface, the pillars separate the light guide plate and the image sensor apart from each other, and the second surface is bonded to the light guide plate. According to an embodiment, since the light guide plate acts in place of a filter element, it is possible to manufacture in ultrasmall size and achieve multiple fluorescence imaging without replacing a filter.

High resolution fluorescence imaging device and method for manufacturing the same

An ultrasonic diagnosis and therapy apparatus according to an embodiment may include an ultrasound output unit including a plurality of ultrasound output elements, a circuit board that can be attached and detached through a connecting board connected to the ultrasound output unit to determine a function of the ultrasound output unit, and a control unit configured to control a setting value of each of the plurality of ultrasound output elements, wherein therapy and diagnosis functions are selectively or simultaneously implemented by changing the circuit board. With the ultrasonic diagnosis and therapy apparatus, it is possible to selectively or simultaneously implement the therapy and diagnosis functions by selectively mounting different types of circuit boards that determine the type and function of ultrasound outputted from the ultrasonic transducers.

Ultrasonic therapy and diagnosis apparatus implementing multiple functions using detachable circuit boards

The present disclosure relates to an apparatus and a method for extracting genome, capable of acquiring a sufficient amount of genome for genetic analysis with high extraction efficiency, even with a small amount of target sample.

Apparatus and method for extracting genome using ultrasound transducer and magnetic bead

The present disclosure relates to an apparatus and a method for manufacturing a channel-coupled scaffold. The present disclosure provides a method for manufacturing a channel-coupled scaffold, which includes: (1) a step of compressing a first elastic substrate which includes a groove on the surface of the substrate to close the groove; (2) a step of loading a scaffold composition onto the closed groove; and (3) a step of restoring the elastic substrate. The present disclosure also provides an apparatus for manufacturing a channel-coupled scaffold, which includes: a first elastic substrate which includes a groove on the surface of the substrate and onto which a scaffold composition is loaded: and a compression module which compresses the width of the groove of the elastic substrate to close it. The apparatus or method may accumulate a microchannel controlling local mass transfer, and align a collagen fiber in the scaffold at the same time.

Apparatus and method for manufacturing channel-coupled scaffold

A porous structure according to the present invention has a polymerase chain reaction (PCT) primer inside pores thereof, and hence, even an inner portion thereof can be used unlike general structures of which only surfaces are used for amplification and detection, thereby maximizing reactivity. In addition, the differentiating of the kinds of primers contained in respective structures leads to detection of several kinds of target nucleic acids at the same and real-time analysis thereof at the same time, and thus is useful for multiplex real-time PCR.

Porous structure and method for manufacturing same

A hydrogel-based interdigitated microelectrode biosensor is disclosed. The hydrogel-based interdigitated microelectrode biosensor includes: a first interdigitated microelectrode having a plurality of first protrusion electrodes arranged in a comb-like shape on a substrate; a second interdigitated microelectrode facing the first interdigitated microelectrode and having a plurality of second protrusion electrodes arranged in a comb-like shape on the substrate, the second protrusion electrodes being arranged alternately with the first protrusion electrodes of the first interdigitated microelectrode; and a hydrogel filled in a space between the first and second interdigitated microelectrodes arranged alternately with each other. The hydrogel is provided between the interdigitated microelectrodes such that the presence and concentration of a biological substance, such as a protein, are detected by measuring the impedance between the interdigitated microelectrodes.

Hydrogel-based interdigitated microelectrode biosensor

Provided are a neurovascular unit (NVU)-on-a-chip and a method of fabricating the same, which 3-dimensionally integrates various human brain cells in a microfluidic platform by using a brain cell co-culture technique so as to simulate a similar environment to the human brain in vitro. The NVU-on-a-chip includes an extracellular matrix (ECM) simulation material () in a gel state; and at least one channel () which passes through the ECM simulation material () and perfuses a culture medium, in which the ECM simulation material () contains a plurality of types of human brain cells on an outer side of the channel (), a brain microvessel endothelial cell lining () is formed on an inner side of the channel (), and the plurality of types of human brain cells and the brain microvessel endothelial cell lining () contact each other through the channel () to simulate a blood brain barrier (BBB) of a human brain and a neurovascular unit (NVU) of the human brain including the BBB.

Neurovascular unit(NVU)-on-a-chip and method of fabricating the same

The present disclosure relates to stretching apparatus and method for aligning microfibrils. Specifically, the present disclosure provides an apparatus for aligning microfibrils along a single direction, which includes: a first elastic substrate onto which a composition containing microfibrils is loaded; and a stretching module which stretches the width of the elastic substrate. In accordance with the apparatus the present disclosure, microfibrils or cells may be aligned along a particular direction simply by pulling and then releasing the elastic substrate. The present disclosure is also useful for culturing of the aligned cells because the physiological activity of the cells can be maintained and cytotoxicity can be prevented.

Stretching apparatus and method for aligning microfibrils

A nerve electrode that is inserted into a living body and that is configured to attach to nerves is provided. The nerve electrode that is inserted into a living body and that is configured to attach to nerves includes: i) a flexible substrate; ii) a plurality of electrodes that are separately positioned on the flexible substrate; and iii) an insulating layer that is positioned at a separation space of the plurality of electrodes and that insulates the plurality of electrodes. The plurality of electrodes include i) at least one linear electrode, and ii) a planar electrode that is separated from the linear electrode. An anti-inflammatory drug transfer layer is positioned on the planar electrode.

Nerve electrode provided with anti-inflammatory drug and method of manufacturing the same

Growing community of inventors

Seoul, South Korea

Nakwon Choi