Andcare, Inc.

Other

Esa Biosciences, Inc.

Najih Naser

John P O'Daly

Robert W Henkens

Marek Wojciechowski

Steven E Wegner

Honghua Zhang

R Michael Roe

Thomas N Stewart

Deborah M Thompson

Rebecca Sundseth

Junguo Zhao

Susan E Morris

Michael A Harpold

Terence M McCaffrey

An electrochemical detection system which specifically detects selected nucleic acid segments is described. The system utilizes biological probes such as nucleic acid or peptide nucleic acid probes which are complementary to and specifically hybridize with selected nucleic acid segments in order to generate a measurable current when an amperometric potential is applied. The electrochemical signal can be quantified.

Electrochemical detection of nucleic acid sequences

The present invention provides a new device for use in measuring lead levels in biological and environmental samples. Using square wave coulometry and colloidal gold particles impregnated on carbon electrodes, the present invention provides a rapid, reliable, portable and inexpensive means of detecting low lead levels. The colloidal gold modified electrodes have microelectrode array characteristics and produce significantly higher stripping detection signals for lead than are produced at bulk gold electrode surfaces. The method is effective in determining levels of lead down to at least 5 .mu.g/dL in blood samples as small as 10 .mu.L.

Colloidal-gold electrosensor measuring device

Growing community of inventors

Orlando, FL, United States of America

Najih Naser