University of California

Naiqing Zhang

Abraham Phillip Lee

James Friend

Gopesh Tilvawala

Roger Shih

Wei-Feng Fang

Jiyang Mei

Articles of manufacture, including an apparatus for omnidirectional spiral surface acoustic wave generation, are provided. An acoustic wave device that generates a plurality of acoustic wave includes a piezoelectric material to convert electric energy into the plurality of acoustic waves. The acoustic wave device also includes a transducer. The transducer includes a plurality of fingers arranged in a spiral formation. The plurality of acoustic waves induce acoustic streaming along the piezoelectric material in multiple directions to isolate a fluid component within a fluid located on the acoustic wave device.

Omnidirectional spiral surface acoustic wave generation

A method of encapsulating a solid sample in a droplet, the method including flowing a continuous phase through a first fluid channel at a first flow rate; flowing a dispersed phase through a second fluid channel at a second flow rate, the dispersed phase including a plurality of particles, cells or beads; trapping the plurality of particles, cells or beads in a mixing region that receives the dispersed phase and the continuous phase; and reducing the first flow rate to encapsulate the trapped particles, cells or beads in droplets of the dispersed phase generated when the dispersed phase and the continuous phase exit the mixing region through an orifice.

Enhanced cell/bead encapsulation methods and apparatuses

Growing community of inventors

San Diego, CA, United States of America

Naiqing Zhang