Bgi Shenzhen

Mgi Tech Co., Ltd.

Genoimmune Therapeutics Co., Ltd.

Naibo Yang

Handong Li

Radoje Drmanac

Bo Li

Snezana Drmanac

Matthew J Callow

Xun Xu

Yong Hou

Shuntao Luo

Xiumei Lin

Ting An

Leon Eckhardt

Chengchi Chao

Zhen Cheng

Wei Zhang

Xiao Liu

Geng Liu

Guanglei Li

Zhe Ren

Dongli Li

Chao Nie

Ruifang Zhang

Xiaojing Zeng

Xinyang Li

Si Qiu

Chongming Jiang

The invention provides compositions and methods for sequencing nucleic acids and other applications. In sequencing by synthesis, unlabeled reversible terminators are incorporated by a polymerase in each cycle, then labeled after incorporation by binding to the reversible terminator a directly or indirectly labeled antibody or other affinity reagent.

Nucleic acid sequencing using affinity reagents

Provided are a tumour antigen polypeptide having the amino acid sequence as shown in SEQ ID NO: 2 or a variant thereof; a nucleic acid encoding same; a nucleic acid construct, an expression vector, and a host cell comprising the encoding nucleic acid; and an antigen presenting cell presenting the tumour antigen polypeptide on the cell surface and an immune effector cell thereof. Also provided is the use of the polypeptide, nucleic acid, antigen presenting cell or immune effector cell in the diagnosis, prevention and treatment of cancers.

Col14A1-derived tumor antigen polypeptide and use thereof

Provided are a tumor antigen polypeptide having the amino acid sequence as shown in SEQ ID NO: 2 or a variant thereof; a nucleic acid encoding the same; a nucleic acid construct, an expression vector, and a host cell containing the encoding nucleic acid; and an antigen presenting cell presenting the tumor antigen polypeptide on the cell surface and an immune effector cell thereof. Also provided is the use of the polypeptide, nucleic acid, antigen presenting cell or immune effector cell in the diagnosis, prevention and treatment of cancers.

CACNA1H-derived tumor antigen polypeptide and use thereof

Provided are a method for screening for nanobodies and a corresponding system. The method uses polymerase chain reactions and cDNA 5' end rapid amplification technology to screen for and obtain nanobodies. The experiment cycle requires only approximately 21 days.

Method and system for screening nanobody

Growing community of inventors

Guangdong, China

Naibo Yang