Georgetown University

Nova Southeastern University

Washington University

Nagarajan Pattabiraman

Kuppuswamy Nagarajan

Radhakrishnan Padmanabhan

Appu Rathinavelu

Niklaus Mueller

Sivanesan Dakshanamurthy

Ajit Kumar

Jayalakshmi Sridhar

Sivanesan Dakshanamurhty

The disclosure teaches antagonists of Hepatitis C Virus (HCV) derived microRNA, which are useful in methods for treating and protecting against HCV-mediated hepatocellular carcinogenesis.

Blocking Hepatitis C Virus infection associated liver tumor development with HCV-specific antisense RNA

Methods of treating, preventing, and/or ameliorating ainfection in a subject are disclosed. The methods comprise administering to the subject a therapeutically effective amount of ainhibitor, e.g., aserine protease inhibitor. These methods are useful in treating, preventing, and/or amelioratinginfections such as, for example, West Nile Virus, Dengue Virus, and Japanese Encephalitis Virus.

Flavivirus inhibitors and methods of their use

Methods of treating, preventing, and/or ameliorating a Flavivirus infection in a subject are disclosed. The methods comprise administering to the subject a therapeutically effective amount of a Flavivirus inhibitor, e.g., a Flavivirus serine protease inhibitor. These methods are useful in treating, preventing, and/or ameliorating Flavivurs infections such as, for example, West Nile Virus, Dengue Virus, and Japanese Encephalitis Virus.

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The present application describes isoindoles and derivatives thereof, or pharmaceutically acceptable salt forms thereof, which are useful inhibitors of VEGFR.

Vascular endothelial receptor specific inhibitors

Specific inhibitors for vascular endothelial growth factor receptors

Growing community of inventors

North Potomac, MD, United States of America

Nagarajan Pattabiraman