Lg Household & Health Care Ltd.

Lg Chem, Ltd

Tai Guk Pharm. Ind. Co., Ltd.

Nae Gyu Kang

Sung Soo Yoon

Jeong Ae Yoon

Su Jeong Kim

Sun Hwa Lee

Chang Hwan Ju

Woo Sun Shim

Jung Yup Kim

Kyung Oh Kim

Sang Hwa Lee

Jung A Kim

Seong Kil Son

Sangmin Lee

Seol Hoon Lee

Eu Gene Hur

Oun Young Lee

Jun Mun Lee

Seong Heon Hong

Jin Hyun Kim

Seo Hun Roh

Seon Guk Choi

Sang-Hun Song

Hyun-Sub Park

Dohyuk Yoo

Jeongrae Lee

Soo Gyu Choi

Provided is a brightening use of a composition including sodium pyruvate and one or more selected from the group consisting of urea and hydroxyethyl urea. Since the composition exhibits a synergistic brightening effect, even when a low concentration of sodium pyruvate is included, a brightening effect at the same level as when a high concentration of sodium pyruvate is used can be obtained. Therefore, the composition can be effectively applied in cosmetics, medicines, external preparations, and the like.

Brightening cosmetic composition comprising sodium pyruvate as active ingredient

The present application relates to an amphiphilic polymer and a method for producing the same. The present application also relates to micelles comprising the amphiphilic polymer and a method for producing the same. The amphiphilic polymer of the present application can have excellent dispersion properties while effectively encapsulating the drug.

Amphiphilic polymer

The present application relates to an amphiphilic triblock polymer and micelles comprising the amphiphilic triblock polymer. The amphiphilic triblock polymer of the present application can have excellent dispersion properties and excellent water solubility while effectively encapsulating the drug.

Amphiphilic triblock polymer

The present application relates to an amphiphilic polymer and a method of preparing the same. Furthermore, the present application relates to a micelle including a drug encapsulated by the amphiphilic polymer and a composition including the same. The amphiphilic polymer according to the present application has excellent drug encapsulation properties as well as good dispersion properties in an aqueous solution.

The present application relates to a micelle comprising a drug encapsulated by an amphiphilic polymer and a composition comprising the same. The micelle of the present application has an excellent dispersion property on an aqueous solution and a superior percutaneous absorption characteristic on preparing a formulation.

The present invention relates to a polynucleotide encoding a fusion protein, an expression vector comprising the polynucleotide, a transformant comprising the expression vector, a method for preparing the fusion protein, and a method for improving skin conditions.

Polynucleotide encoding a fusion protein for improving skin conditions

The present invention relates to a fusion protein comprising a skin-penetrating peptide, a polynucleotide encoding the fusion protein, an expression vector comprising the polynucleotide, a transformant comprising the expression vector, a method for preparing the fusion protein, a cosmetic composition for improving skin conditions, which comprises the fusion protein, and a pharmaceutical composition for external skin use, which comprises the fusion protein. The fusion protein of the invention comprises a skin-penetrating peptide bound to a physiologically active protein. The fusion protein significantly enhances the skin penetration and skin retention of the physiologically active protein while maintaining or enhancing the ability of the physiologically active protein to synthesize a material showing physiologically active effects. Thus, it can be widely used as an active ingredient in functional cosmetic compositions and pharmaceutical compositions for external skin use.

Cosmetic composition for improving skin conditions comprising fusion protein

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Daejeon, South Korea

Nae Gyu Kang