Nexmed (holdings) Incorporated

Nadir B&uuml;y&uuml;ktimkin

James L Yeager

Servet B&uuml;y&uuml;ktimkin

The invention provides compositions and methods suitable for ameliorating female sexual dysfunction, and in particular, female sexual arousal disorder. In one embodiment, the invention provides a semisolid composition suitable for topical application comprising: an effective amount of a vasoactive prostaglandin, a polysaccharide thickener, a lipophilic component, and an acidic buffer system.

Compositions and methods for amelioration of human female sexual dysfunction

A topical composition of a semi-solid consistency suitable is provided for transdermal application of prostaglandin E . The composition comprises prostaglandin E , a penetration enhancer, a polysaccharide gum, a lipophilic compound, and an acidic buffer system. The penetration enhancer is an acid addition salt of an alkyl-2-(substituted amino)-alkanoate ester, of a (substituted amino)-alkanol alkanoate, or of a mixture thereof. The lipophilic compound may be an aliphatic C to C alcohol, an aliphatic C to C ester, or a mixture of these. The composition includes a buffer system capable of providing a buffered pH value for said composition in the range of about 3 to about 7.4.

Growing community of inventors

Robbinsville, NJ, United States of America

Nadir Büyüktimkin

Growing community of inventors

Robbinsville, NJ, United States of America

Nadir B&uuml;y&uuml;ktimkin

Nadir Büyüktimkin