Uchicago Argonne, LLC

Nada M Dimitrijevic

Tijana Rajh

Elena A Rozhkova

YuPo J Lin

Seth B Darling

Seth W Snyder

Sanja Tepavcevic

Richard D Schaller

Peng Wang

Steven J Sibener

Norman F Sather

Harry C Fry

Tamara Koritarov

Bartosz Gryzbowski

Shankar G Balasubramanian

A nanostructure comprises a MOX NP and a bidentate ligand on a surface of the MOX NP. A cancer recognition molecule is covalent coupled to the surface of the MOX NP via the bidentate ligand. A biocatalyst is also coupled to the surface of the MOX nanoparticle via the bidentate ligand. The cancer recognition molecule includes a structure configured to selectively recognize a corresponding antigen on a surface of a cancer cell and bind to the antigen. The biocatalyst is structured to selectively catalyze the oxidation of a light emitting compound to produce photons. The photons transform the MOX NPs into an excited state such that the MOX NPs generate reactive oxygen species (ROS) in the vicinity of the cancer cells in the excited state. The reactive oxygen species lyse or cause apoptosis in the cancer cells in situ. The biocatalyst includes luciferase and the light emitting compound includes luciferin.

Metal oxide nanoparticle for cell lysis

Aspects of the disclosure relate to an efficient entirely man-made nanobio hybrid fabricated through cell-free expression of transmembrane proton pump followed by assembly of the synthetic protein architecture with semiconductor nanoparticles for photocatalytic Hevolution. The system produces Hat a turnover rate of 240 &#x3bc;mol of H(&#x3bc;mol protein)hunder green and 17.74 mmol of H(&#x3bc;mol protein)hunder white light at ambient conditions, in water at neutral pH with methanol as a sacrificial electron donor. Robsutness and flexibility of this approach allows for systemic manipulation at nanoparticle-bio interface toward directed evolution of energy materials and devices.

Semiconductor-metal nanoparticle hybrids with natural and artificial proton pump for hydrogen production

A hybrid photovoltaic cell comprising a composite substrate of a nanotube or nanorod array of metal oxide infiltrated with a monomer precursor and subsequently polymerized in situ via UV irradiation. In an embodiment, the photovoltaic cell comprises an electron accepting TiOnanotube array infiltrated with a photo-sensitive electron donating conjugated polymer. The conjugated polymer may be formed in situ through UV irradiation polymerizing a monomer precursor such as 2,5-diiodothiophene (DIT).

Hybrid solar cells via UV-polymerization of polymer precursor

The invention provides a system for separating oppositely-charged charge carriers, the substrate comprising a semiconductor; a ligand in electrical communication with said semiconductor; an ion-exchange resin attached to the semiconductor; an ion-exchange membrane; and an electrical conduit attaching said resin to said membrane. Also provided is a method for producing hydrogen gas, comprising: inducing charge separation in semiconductor particles so as to produce electrons and holes; oxidizing water with the holes to produce oxygen ions and protons, wherein the protons are sequestered from the oxygen ions as the protons are produced; and directing the sequestered protons to a cathode. The invention also provides a method to produce electricity comprising, inducing charge separation in semiconductor particles so as to produce electrons and holes, and completing the circuit with an electron hole transporter.

Integrated device and substrate for separating charged carriers and reducing photocorrosion and method for the photoelectrochemical production of electricity and photocatalytic production of hydrogen

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Lemont, IL, United States of America

Nada M Dimitrijevic