Mdsg Innovation Ltd.

Xcardia Innovation Ltd

Naama Winetraub

Benny Rousso

Lior Eshel

Assaf Erell

Boaz Rippin

Yonatan Levi

Rodny Zarini

David Maier Neustadter

The present invention relates to means and methods for modifying renal function in a subject, comprising selecting a patient requiring an increment in renal function; emitting a quantity of ultrasound radiation, enough to provide an increment in renal function, to at least one part of a kidney for a period of time from about 1 hours to about 30 days.

Apparatus and method for treating kidneys

The invention relates to a cardiac lead extraction device, comprising: a handle; an elongated body having a first proximal end, a first distal end, and a first lumen extending from said first proximal end toward said first distal end, said lumen sized and shaped to fit over a cardiac lead; a controllable bendable flexible portion more flexible that said elongated body and having a second proximal end, a second distal end and a second lumen extending from said second proximal end toward said second distal end, said lumen sized and shaped to fit over a cardiac lead; said second proximal end interconnected to said first distal end; said second distal end interconnected to an operational distal end; wherein said operational distal end comprises at least one lead extraction assistive tool, said lead extraction helping tool is activated by a motor located at said handle or proximally to said handle.

Cardiac lead extraction device

A method and/or system are provided for improving kidney function and/or increasing Glomerular Filtration Rate (GFR) of the renal system, by applying acoustic and/or ultrasonic energy to one or more of the kidneys. The method suggests either focused or non-focused (or combined) energy delivery, optionally in a noninvasive approach, which could also be implemented invasively and/or by implantable device. Potential applications of this technique, include, but are not restricted to, treatment of renal disorders such as CKD (Chronic Kidney Disease) and/or AKI (Acute Kidney Injury), short term or long term intervention in kidney function for therapeutic or diagnostic purposes, modifying urine output in heart failure, modulating blood volume and/or pressure, and modulating clearance of compounds in the blood are typically difficult to extract from the kidneys, such as iodine, other imaging contrast media, and similar compounds.

An aspect of some embodiments of the invention relate to a system for tissue characterization using an acousto-electric effect comprising: at least one ultrasonic waveform generator; at least one waveform generation controller; at least one set of electrodes; at least one electric signal amplification circuitry connectable to at least one of said at least one set of electrodes to generate an amplified signal; and at least one signal processing unit for analyzing said amplified signal and to generate information related to properties of multiple locations within a target tissue; wherein at least one of said multiple location has no direct contact with any electrode, and wherein said properties of said multiple locations are obtained within up to 10 milliseconds per location on average.

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Holon, Israel

Naama Winetraub