Daewoong Pharmaceutical Co., Ltd.

Seoul National University

In Therapeutics

Myunggi Jung

Sun Ah Jun

Chun Ho Lee

Hyo Shin Kim

Hyo-Soo Kim

Ji Duck Kim

Ja Kyung Yoo

Ji Sung Yoon

Hyung-Geun Lee

Nora Lee

Hyung Geun Lee

Inwoo Kim

Il-Hwan Kim

Sung-Young Kim

The present invention relates to a compound represented by Chemical Formula 1, or a pharmaceutically acceptable salt thereof. The compound according to the present invention can be usefully used for the prevention or treatment of cardiovascular diseases. 

Phenyl phthalazine derivative, method for the preparation thereof, and pharmaceutical composition comprising the same

The present invention relates to a compound having a blocking effect against sodium ion channels, particularly Nav1.7, a preparation method thereof and use thereof. The compound represented by the Formula 1 or a pharmaceutically acceptable salt, hydrate, solvate or isomer thereof can be effectively used in the prevention or treatment of pains, for example, acute pain, chronic pain, pain from nervous disease, postoperative pain, migraine, arthralgia, neuropathy, nerve injury, diabetic neuropathy, neuropathic disease, epilepsy, arrhythmia, myotonia, ataxia, multiple sclerosis, irritable bowel syndrome, urinary incontinence, visceral pain, depression, erythromelalgia, paroxysmal extreme pain disorder (PEPD).

Sodium channel blockers

The invention relates to a compound represented by Chemical Formula 1, below, a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the compound or salt. The compound of the invention or pharmaceutically acceptable salts thereof can be used for the prevention or treatment of sodium channel blocker-related diseases. 

Substituted benzenesulfonamides as sodium channel blockers

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Gyeonggi-do, South Korea

Myunggi Jung